Explore IL-1F7/IL-37/IL37 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T96845
|
| Target Name |
IL-1F7/IL-37/IL37
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
27178
|
| Gene ID |
100052470 (Equus caballus), 100686057 (Canis lupus familiaris), 27178 (Homo sapiens), 700579 (Macaca mulatta)
786493 (Bos taurus)
|
| Target Alternative Names |
IL37,FIL1,FIL1Z,IL-1H,IL-23,IL-37,IL1F7,IL1H4,IL-1F7,IL-1H4,IL1RP1,IL-1RP1,FIL1(ZETA)
|
| Uniprot Accession |
Q9NZH6
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor
|
| Gene Ensembl |
ENSECAG00000015732, ENSCAFG00845011516, ENSG00000125571, ENSMMUG00000005922, ENSBTAG00000013675
|
| Target Classification |
|
Pre-made viral vector of IL-1F7/IL-37/IL37 cDNA Clones/ORF Plasmid
IL-1F7/IL-37/IL37 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo27178 | Pre-made Human IL37/FIL1/FIL1Z siRNA oligo Duplex | 27178 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700579 | Pre-made Cynomolgus/Rhesus macaque IL37 siRNA oligo Duplex | 700579 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100686057 | Pre-made Dog/Canine IL37 siRNA oligo Duplex | 100686057 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo786493 | Pre-made Bovines/Cattle IL37/IL1F7 siRNA oligo Duplex | 786493 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052470 | Pre-made Equine/Horse IL37 siRNA oligo Duplex | 100052470 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-1F7/IL-37/IL37 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T96845-Ab | Human | Anti-Human IL-1F7/IL-37/IL37 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T96845-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-1F7/IL-37/IL37 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T96845-Ab | Dog/Canine | Anti-Dog/Canine IL-1F7/IL-37/IL37 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T96845-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-1F7/IL-37/IL37 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T96845-Ab | Equine/Horse | Anti-Equine/Horse IL-1F7/IL-37/IL37 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-1F7/IL-37/IL37 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T96845-Ag | Human | Human IL-1F7/IL-37/IL37 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T96845-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-1F7/IL-37/IL37 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T96845-Ag | Dog/Canine | Dog/Canine IL-1F7/IL-37/IL37 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T96845-Ag | Bovines/Cattle | Bovines/Cattle IL-1F7/IL-37/IL37 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T96845-Ag | Equine/Horse | Equine/Horse IL-1F7/IL-37/IL37 recombinant protein | Mammalian cell | Detail |
