Recombinant multi-species IL-1F7/IL-37/IL37 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-1F7/IL-37/IL37 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
The Alternative Names of target: IL-1F7, IL-37, IL37,Interleukin-37,IL-37,FIL1 zeta, IL-1X, Interleukin-1 family member 7 (IL-1F7), Interleukin-1 homolog 4 (IL-1H, IL-1H4), Interleukin-1 zeta (IL-1 zeta), Interleukin-1-related protein (IL-1RP1),FIL1,FIL1Z,IL-1H,IL-23,IL-37,IL1F7,IL1H4,IL-1F7,IL-1H4,IL1RP1,IL-1RP1,FIL1(ZETA)

Target products collectionGo to IL-1F7/IL-37/IL37 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T96845-Ab-1/ GM-Tg-hg-T96845-Ab-2 Human IL-1F7/IL-37/IL37 protein Human
GM-Tg-rg-T96845-Ab-1/ GM-Tg-rg-T96845-Ab-2 Rat IL-1F7/IL-37/IL37 protein Rat
GM-Tg-mg-T96845-Ab-1/ GM-Tg-mg-T96845-Ab-2 Mouse IL-1F7/IL-37/IL37 protein Mouse
GM-Tg-cynog-T96845-Ab-1/ GM-Tg-cynog-T96845-Ab-2 Cynomolgus/Rhesus macaque IL-1F7/IL-37/IL37 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T96845-Ab-1/ GM-Tg-felg-T96845-Ab-2 Feline IL-1F7/IL-37/IL37 protein Feline
GM-Tg-cang-T96845-Ab-1/ GM-Tg-cang-T96845-Ab-2 Canine IL-1F7/IL-37/IL37 protein Canine
GM-Tg-bovg-T96845-Ab-1/ GM-Tg-bovg-T96845-Ab-2 Bovine IL-1F7/IL-37/IL37 protein Bovine
GM-Tg-equg-T96845-Ab-1/ GM-Tg-equg-T96845-Ab-2 Equine IL-1F7/IL-37/IL37 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T96845-Ab-1/ GM-Tg-hg-T96845-Ab-2; GM-Tg-rg-T96845-Ab-1/ GM-Tg-rg-T96845-Ab-2;
GM-Tg-mg-T96845-Ab-1/ GM-Tg-mg-T96845-Ab-2; GM-Tg-cynog-T96845-Ab-1/ GM-Tg-cynog-T96845-Ab-2;
GM-Tg-felg-T96845-Ab-1/ GM-Tg-felg-T96845-Ab-2; GM-Tg-cang-T96845-Ab-1/ GM-Tg-cang-T96845-Ab-2;
GM-Tg-bovg-T96845-Ab-1/ GM-Tg-bovg-T96845-Ab-2; GM-Tg-equg-T96845-Ab-1/ GM-Tg-equg-T96845-Ab-2
Products Name IL-1F7/IL-37/IL37 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IL-1F7/IL-37/IL37
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-1F7/IL-37/IL37 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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