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(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T31621
|
| Target Name |
FGF2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2247
|
| Gene ID |
100033955 (Equus caballus), 100135772 (Felis catus), 14173 (Mus musculus), 2247 (Homo sapiens)
281161 (Bos taurus), 403857 (Canis lupus familiaris), 54250 (Rattus norvegicus), 574136 (Macaca mulatta)
|
| Target Alternative Names |
FGF2,Fgf2,Fgfb,bFGF,Fgf-2,Fgf2a,BFGF,FGFB,FGF-2,HBGF-2
|
| Uniprot Accession |
P15655,P09038,P03969,P13109
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
|
| Disease |
cancer, Breast Cancer
|
| Disease from KEGG |
EGFR tyrosine kinase inhibitor resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Melanoma, Breast cancer, Gastric cancer
|
| Gene Ensembl |
ENSMUSG00000037225, ENSG00000138685
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of FGF2 cDNA Clones/ORF Plasmid
FGF2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2247 | Pre-made Human FGF2/BFGF/FGFB siRNA oligo Duplex | 2247 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo54250 | Pre-made Rat Fgf2/bFGF/Fgf-2 siRNA oligo Duplex | 54250 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14173 | Pre-made Mouse Fgf2/Fgfb/bFGF siRNA oligo Duplex | 14173 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574136 | Pre-made Cynomolgus/Rhesus macaque FGF2 siRNA oligo Duplex | 574136 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100135772 | Pre-made Cat/Feline FGF2 siRNA oligo Duplex | 100135772 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403857 | Pre-made Dog/Canine FGF2/BFGF siRNA oligo Duplex | 403857 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281161 | Pre-made Bovines/Cattle FGF2/BFGF/FGF-2 siRNA oligo Duplex | 281161 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033955 | Pre-made Equine/Horse FGF2 siRNA oligo Duplex | 100033955 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FGF2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T31621-Ab | Human | Anti-Human FGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T31621-Ab | Rat | Anti-Rat FGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T31621-Ab | Mouse | Anti-Mouse FGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T31621-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T31621-Ab | Cat/Feline | Anti-Cat/Feline FGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T31621-Ab | Dog/Canine | Anti-Dog/Canine FGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T31621-Ab | Bovines/Cattle | Anti-Bovines/Cattle FGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T31621-Ab | Equine/Horse | Anti-Equine/Horse FGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
FGF2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T31621-Ag | Human | Human FGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T31621-Ag | Rat | Rat FGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T31621-Ag | Mouse | Mouse FGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T31621-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T31621-Ag | Cat/Feline | Cat/Feline FGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T31621-Ag | Dog/Canine | Dog/Canine FGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T31621-Ag | Bovines/Cattle | Bovines/Cattle FGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T31621-Ag | Equine/Horse | Equine/Horse FGF2 recombinant protein | Mammalian cell | Detail |
