Recombinant multi-species FGF2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008]
The Alternative Names of target: FGF2,Fibroblast growth factor 2,FGF-2,Basic fibroblast growth factor (bFGF), Heparin-binding growth factor 2 (HBGF-2),BFGF,FGFB,FGF-2,HBGF-2

Target products collectionGo to FGF2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T31621-Ab-1/ GM-Tg-hg-T31621-Ab-2 Human FGF2 protein Human
GM-Tg-rg-T31621-Ab-1/ GM-Tg-rg-T31621-Ab-2 Rat FGF2 protein Rat
GM-Tg-mg-T31621-Ab-1/ GM-Tg-mg-T31621-Ab-2 Mouse FGF2 protein Mouse
GM-Tg-cynog-T31621-Ab-1/ GM-Tg-cynog-T31621-Ab-2 Cynomolgus/Rhesus macaque FGF2 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T31621-Ab-1/ GM-Tg-felg-T31621-Ab-2 Feline FGF2 protein Feline
GM-Tg-cang-T31621-Ab-1/ GM-Tg-cang-T31621-Ab-2 Canine FGF2 protein Canine
GM-Tg-bovg-T31621-Ab-1/ GM-Tg-bovg-T31621-Ab-2 Bovine FGF2 protein Bovine
GM-Tg-equg-T31621-Ab-1/ GM-Tg-equg-T31621-Ab-2 Equine FGF2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T31621-Ab-1/ GM-Tg-hg-T31621-Ab-2; GM-Tg-rg-T31621-Ab-1/ GM-Tg-rg-T31621-Ab-2;
GM-Tg-mg-T31621-Ab-1/ GM-Tg-mg-T31621-Ab-2; GM-Tg-cynog-T31621-Ab-1/ GM-Tg-cynog-T31621-Ab-2;
GM-Tg-felg-T31621-Ab-1/ GM-Tg-felg-T31621-Ab-2; GM-Tg-cang-T31621-Ab-1/ GM-Tg-cang-T31621-Ab-2;
GM-Tg-bovg-T31621-Ab-1/ GM-Tg-bovg-T31621-Ab-2; GM-Tg-equg-T31621-Ab-1/ GM-Tg-equg-T31621-Ab-2
Products Name FGF2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FGF2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.