CXCL12/SDF-1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore CXCL12/SDF-1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Secreted Protein/Potential Cytokines.
This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

Target ID	GM-T04773
Target Name	CXCL12/SDF-1
Gene Group ldentifer （Target Gene ID in Homo species)	6387
Gene ID	100049872 (Equus caballus), 20315 (Mus musculus), 24772 (Rattus norvegicus), 449622 (Canis lupus familiaris) 493806 (Felis catus), 574334 (Macaca mulatta), 613811 (Bos taurus), 6387 (Homo sapiens)
Target Alternative Names	C-X-C motif chemokine 12,CXCL12,Cxcl12,IRH,Intercrine reduced in hepatomas (IRH,PBSF,Pbsf,Pre-B cell growth-stimulating factor (PBSF),SCYB12,SDF-1,SDF1,Scyb12,Sdf1,Stromal cell-derived factor 1,TLSF,TPAR1,Tlsf,Tpar1,hIRH),hSDF-1
Uniprot Accession	P40224,O62657,P48061
Protein Sub-location	Secreted Protein/Potential Cytokines
Category	Therapeutics Target, Immuno-oncology Target, Cytokine Target
Disease	cancer
Disease from KEGG	Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, NF-kappa B signaling pathway, Axon guidance, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer, Rheumatoid arthritis
Gene Ensembl	ENSECAG00000019551, ENSMUSG00000061353, ENSCAFG00845026834, ENSMMUG00000012181, ENSBTAG00000005077, ENSG00000107562
Target Classification	Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)

Pre-made viral vector of CXCL12/SDF-1 cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLV000007	Human CXCL12/IRH/PBSF Lentivirus plasmid	NM_199168.3	6387	Human	Lentivirus plasmid	ZsGreen	Null	CMV	Detail
pGMAP000581	Human CXCL12/IRH/PBSF Adenovirus plasmid	NM199168	6387	Human	Adenovirus plasmid	GFP	3xflag (C-Terminal)	EF1	Detail
vGMAP000581	Human CXCL12/IRH/PBSF Adenovirus particle	NM199168	6387	Human	Adenovirus particle	GFP	3xflag (C-Terminal)	EF1	Detail
vGMAAV000139	Human CXCL12/IRH/PBSF Adeno-associate virus(AAV) particle	NM_000609	6387	Human	Adeno-associate virus(AAV) particle	GFP	3xflag (C-Terminal)	CMV	Detail
vGMAD000581	Human CXCL12/IRH/PBSF Adenovirus particle	NM_001178134.1	6387	Human	Adenovirus particle	GFP	3xflag (C-Terminal)	EF1	Detail
vGMLV002285	Human CXCL12/IRH/PBSF Lentivirus particle	NM_001033886.2	6387	Human	Lentivirus particle	Null	3xflag (C-Terminal)	CMV	Detail
vGMLV000955	Human CXCL12/IRH/PBSF Lentivirus particle	NM_001178134.2	6387	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV000007	Human CXCL12/IRH/PBSF Lentivirus particle	NM_199168.3	6387	Human	Lentivirus particle	ZsGreen	Null	CMV	Detail
pGMPC001800	Human CXCL12/IRH/PBSF Mammalian (Non-Viral Vector) plasmid	NM_000609.7	6387	Human	Mammalian (Non-Viral Vector) plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
pGMAAV000139	Human CXCL12/IRH/PBSF Adeno-associate virus(AAV) plasmid	NM_000609	6387	Human	Adeno-associate virus(AAV) plasmid	GFP	3xflag (C-Terminal)	CMV	Detail
pGMAD000581	Human CXCL12/IRH/PBSF Adenovirus plasmid	NM_001178134.1	6387	Human	Adenovirus plasmid	GFP	3xflag (C-Terminal)	EF1	Detail
pGMLV002285	Human CXCL12/IRH/PBSF Lentivirus plasmid	NM_001033886.2	6387	Human	Lentivirus plasmid	Null	3xflag (C-Terminal)	CMV	Detail
pGMLV000955	Human CXCL12/IRH/PBSF Lentivirus plasmid	NM_001178134.2	6387	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLV000424	Rat Cxcl12/Sdf1 Lentivirus plasmid	NM_001033883	24772	Rat	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAAV000080	Rat Cxcl12/Sdf1 Adeno-associate virus(AAV) plasmid	NM_022177.3	24772	Rat	Adeno-associate virus(AAV) plasmid	GFP	Null	CMV	Detail
vGMLV000424	Rat Cxcl12/Sdf1 Lentivirus particle	NM_001033883	24772	Rat	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV000647	Rat Cxcl12/Sdf1 Lentivirus particle	NM_022177.3	24772	Rat	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAAV000080	Rat Cxcl12/Sdf1 Adeno-associate virus(AAV) particle	NM_022177.3	24772	Rat	Adeno-associate virus(AAV) particle	GFP	Null	CMV	Detail
pGMLV000647	Rat Cxcl12/Sdf1 Lentivirus plasmid	NM_022177.3	24772	Rat	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAAV001831	Mouse Cxcl12/Pbsf/Scyb12 Adeno-associate virus(AAV) plasmid	NM_013655.4	20315	Mouse	Adeno-associate virus(AAV) plasmid	ZsGreen	6xHis (C-Terminal)	CMV	Detail
pGMLPm000543	Mouse Cxcl12/Pbsf/Scyb12 Lentivirus plasmid	NM_001012477	20315	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV001240	Mouse Cxcl12/PB/Pbsf Lentivirus particle	NM_013655.4	20315	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLV001240	Mouse Cxcl12/PB/Pbsf Lentivirus plasmid	NM_013655.4	20315	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAAV001831	Mouse Cxcl12/Pbsf/Scyb12 Adeno-associate virus(AAV) particle	NM_013655.4	20315	Mouse	Adeno-associate virus(AAV) particle	ZsGreen	6xHis (C-Terminal)	CMV	Detail
vGMLPm000543	Mouse Cxcl12/Pbsf/Scyb12 Lentivirus particle	NM_001012477	20315	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

CXCL12/SDF-1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo6387	Pre-made Human CXCL12/IRH/PBSF siRNA oligo Duplex	6387	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo24772	Pre-made Rat Cxcl12/Sdf1 siRNA oligo Duplex	24772	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo20315	Pre-made Mouse Cxcl12/Pbsf/Sdf1 siRNA oligo Duplex	20315	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo574334	Pre-made Cynomolgus/Rhesus macaque CXCL12 siRNA oligo Duplex	574334	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo493806	Pre-made Cat/Feline CXCL12/SDF1/SDF-1 siRNA oligo Duplex	493806	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo449622	Pre-made Dog/Canine CXCL12/SDF1 siRNA oligo Duplex	449622	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo613811	Pre-made Bovines/Cattle CXCL12/SDF1 siRNA oligo Duplex	613811	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100049872	Pre-made Equine/Horse CXCL12/SDF1 siRNA oligo Duplex	100049872	Equine/Horse	In-vitro grade; in-vivo grade	Detail

CXCL12/SDF-1 antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-T04773-Ab	Human	Anti-Human CXCL12/SDF-1 monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody	Detail
GM-Tg-rg-T04773-Ab	Rat	Anti-Rat CXCL12/SDF-1 monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody	Detail
GM-Tg-mg-T04773-Ab	Mouse	Anti-Mouse CXCL12/SDF-1 monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody	Detail
GM-Tg-cynog-T04773-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque CXCL12/SDF-1 monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody	Detail
GM-Tg-felg-T04773-Ab	Cat/Feline	Anti-Cat/Feline CXCL12/SDF-1 monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody	Detail
GM-Tg-cang-T04773-Ab	Dog/Canine	Anti-Dog/Canine CXCL12/SDF-1 monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody	Detail
GM-Tg-bovg-T04773-Ab	Bovines/Cattle	Anti-Bovines/Cattle CXCL12/SDF-1 monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody	Detail
GM-Tg-equg-T04773-Ab	Equine/Horse	Anti-Equine/Horse CXCL12/SDF-1 monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody	Detail

CXCL12/SDF-1 recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-T04773-Ag	Human	Human CXCL12/SDF-1 recombinant protein	Mammalian cell	Detail
GM-Tg-rg-T04773-Ag	Rat	Rat CXCL12/SDF-1 recombinant protein	Mammalian cell	Detail
GM-Tg-mg-T04773-Ag	Mouse	Mouse CXCL12/SDF-1 recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-T04773-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque CXCL12/SDF-1 recombinant protein	Mammalian cell	Detail
GM-Tg-felg-T04773-Ag	Cat/Feline	Cat/Feline CXCL12/SDF-1 recombinant protein	Mammalian cell	Detail
GM-Tg-cang-T04773-Ag	Dog/Canine	Dog/Canine CXCL12/SDF-1 recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-T04773-Ag	Bovines/Cattle	Bovines/Cattle CXCL12/SDF-1 recombinant protein	Mammalian cell	Detail
GM-Tg-equg-T04773-Ag	Equine/Horse	Equine/Horse CXCL12/SDF-1 recombinant protein	Mammalian cell	Detail