Recombinant multi-species CXCL12/SDF-1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CXCL12/SDF-1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
The Alternative Names of target: C-X-C motif chemokine 12,CXCL12,Cxcl12,IRH,Intercrine reduced in hepatomas (IRH,PBSF,Pbsf,Pre-B cell growth-stimulating factor (PBSF),SCYB12,SDF-1,SDF1,Scyb12,Sdf1,Stromal cell-derived factor 1,TLSF,TPAR1,Tlsf,Tpar1,hIRH),hSDF-1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T04773-Ag-1/ GM-Tg-hg-T04773-Ag-2 | Human CXCL12/SDF-1 protein | Human |
| GM-Tg-rg-T04773-Ag-1/ GM-Tg-rg-T04773-Ag-2 | Rat CXCL12/SDF-1 protein | Rat |
| GM-Tg-mg-T04773-Ag-1/ GM-Tg-mg-T04773-Ag-2 | Mouse CXCL12/SDF-1 protein | Mouse |
| GM-Tg-cynog-T04773-Ag-1/ GM-Tg-cynog-T04773-Ag-2 | Cynomolgus/Rhesus macaque CXCL12/SDF-1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T04773-Ag-1/ GM-Tg-felg-T04773-Ag-2 | Feline CXCL12/SDF-1 protein | Feline |
| GM-Tg-cang-T04773-Ag-1/ GM-Tg-cang-T04773-Ag-2 | Canine CXCL12/SDF-1 protein | Canine |
| GM-Tg-bovg-T04773-Ag-1/ GM-Tg-bovg-T04773-Ag-2 | Bovine CXCL12/SDF-1 protein | Bovine |
| GM-Tg-equg-T04773-Ag-1/ GM-Tg-equg-T04773-Ag-2 | Equine CXCL12/SDF-1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T04773-Ag-1/ GM-Tg-hg-T04773-Ag-2;
GM-Tg-rg-T04773-Ag-1/ GM-Tg-rg-T04773-Ag-2;
GM-Tg-mg-T04773-Ag-1/ GM-Tg-mg-T04773-Ag-2; GM-Tg-cynog-T04773-Ag-1/ GM-Tg-cynog-T04773-Ag-2; GM-Tg-felg-T04773-Ag-1/ GM-Tg-felg-T04773-Ag-2; GM-Tg-cang-T04773-Ag-1/ GM-Tg-cang-T04773-Ag-2; GM-Tg-bovg-T04773-Ag-1/ GM-Tg-bovg-T04773-Ag-2; GM-Tg-equg-T04773-Ag-1/ GM-Tg-equg-T04773-Ag-2 |
| Products Name | CXCL12/SDF-1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CXCL12/SDF-1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CXCL12/SDF-1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.