Human CXCL12/IRH/PBSF ORF/cDNA clone-Adenovirus particle (NM199168)
Cat. No.: vGMAP000581
Pre-made Human CXCL12/IRH/PBSF Adenovirus for CXCL12 overexpression in-vitro and in-vivo. The CXCL12 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified CXCL12-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
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Product information
| Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
| vGMAP000581 | Human CXCL12 Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
| 5E+10PFU (1E+10pfu/ml×5ml) | |||
| 1E+11PFU (1E+10pfu/ml×10ml) | |||
| Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMAP000581 |
| Gene Name | CXCL12 |
| Accession Number | NM199168 |
| Gene ID | 6387 |
| Species | Human |
| Product Type | Adenovirus particle (overexpression) |
| Insert Length | 270 bp |
| Gene Alias | IRH,PBSF,SCYB12,SDF1,TLSF,TPAR1 |
| Fluorescent Reporter | GFP |
| Mammalian Cell Selection | Null |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | EF1 |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGAACGCCAAGGTCGTGGTCGTGCTGGTCCTCGTGCTGACCGCGCTCTGCCTCAGCGACGGGAAGCCCGTCAGCCTGAGCTACAGATGCCCATGCCGATTCTTCGAAAGCCATGTTGCCAGAGCCAACGTCAAGCATCTCAAAATTCTCAACACTCCAAACTGTGCCCTTCAGATTGTAGCCCGGCTGAAGAACAACAACAGACAAGTGTGCATTGACCCGAAGCTAAAGTGGATTCAGGAGTACCTGGAGAAAGCTTTAAACAAGTAA |
| ORF Protein Sequence | MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNK |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Target information
| Target ID | GM-T04773 |
| Target Name | CXCL12/SDF-1 |
|
Gene Group Identifier (Target Gene ID in Homo species) |
6387 |
| Gene ID |
100049872 (Equus caballus), 20315 (Mus musculus), 24772 (Rattus norvegicus), 449622 (Canis lupus familiaris) 493806 (Felis catus), 574334 (Macaca mulatta), 613811 (Bos taurus), 6387 (Homo sapiens) |
| Gene Symbols & Synonyms | CXCL12,Cxcl12,SDF1,Pbsf,Sdf1,Tlsf,Tpar1,Scyb12,SDF-1,IRH,PBSF,TLSF,TPAR1,SCYB12 |
| Target Alternative Names | C-X-C motif chemokine 12,CXCL12,Cxcl12,IRH,Intercrine reduced in hepatomas (IRH,PBSF,Pbsf,Pre-B cell growth-stimulating factor (PBSF),SCYB12,SDF-1,SDF1,Scyb12,Sdf1,Stromal cell-derived factor 1,TLSF,TPAR1,Tlsf,Tpar1,hIRH),hSDF-1 |
| Uniprot Accession |
O62657,P40224,P48061
Additional SwissProt Accessions: P40224,O62657,P48061 |
| Uniprot Entry Name | |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Immuno-oncology Target, Cytokine Target |
| Disease | cancer |
| Disease from KEGG | Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, NF-kappa B signaling pathway, Axon guidance, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer, Rheumatoid arthritis |
| Gene Ensembl | ENSECAG00000019551, ENSMUSG00000061353, ENSCAFG00845026834, ENSMMUG00000012181, ENSBTAG00000005077, ENSG00000107562 |
| Target Classification | Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA) |
About GMVC

GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.


