Explore IL-1F6/IL-36 Alpha/IL36A gene products and cross-species
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. [provided by RefSeq, Nov 2015]
| Target ID |
GM-SE1029
|
| Target Name |
IL-1F6/IL-36 Alpha/IL36A
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
27179
|
| Gene ID |
27179 (Homo sapiens), 296541 (Rattus norvegicus), 705136 (Macaca mulatta)
|
| Target Alternative Names |
FIL1,FIL1 epsilon,FIL1(EPSILON),FIL1E,IL-1F6,IL-36 Alpha,IL1(EPSILON),IL1F6,IL36A,Il1f6,Il36a,Interleukin-1 epsilon (IL-1 epsilon),Interleukin-1 family member 6 (IL-1F6),Interleukin-36 alpha
|
| Uniprot Accession |
Q9UHA7
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSG00000136694, ENSMMUG00000000988
|
Pre-made viral vector of IL-1F6/IL-36 Alpha/IL36A cDNA Clones/ORF Plasmid
IL-1F6/IL-36 Alpha/IL36A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo27179 | Pre-made Human IL36A/FIL1/FIL1E siRNA oligo Duplex | 27179 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo296541 | Pre-made Rat Il36a/Il1f6 siRNA oligo Duplex | 296541 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705136 | Pre-made Cynomolgus/Rhesus macaque IL36A/IL1F6 siRNA oligo Duplex | 705136 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
IL-1F6/IL-36 Alpha/IL36A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1029-Ab | Human | Anti-Human IL-1F6/IL-36 Alpha/IL36A monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE1029-Ab | Rat | Anti-Rat IL-1F6/IL-36 Alpha/IL36A monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE1029-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-1F6/IL-36 Alpha/IL36A monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
IL-1F6/IL-36 Alpha/IL36A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1029-Ag | Human | Human IL-1F6/IL-36 Alpha/IL36A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1029-Ag | Rat | Rat IL-1F6/IL-36 Alpha/IL36A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1029-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-1F6/IL-36 Alpha/IL36A recombinant protein | Mammalian cell | Detail |