Recombinant multi-species IL-1F6/IL-36 Alpha/IL36A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-1F6/IL-36 Alpha/IL36A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. [provided by RefSeq, Nov 2015]
The Alternative Names of target: FIL1,FIL1 epsilon,FIL1(EPSILON),FIL1E,IL-1F6,IL-36 Alpha,IL1(EPSILON),IL1F6,IL36A,Il1f6,Il36a,Interleukin-1 epsilon (IL-1 epsilon),Interleukin-1 family member 6 (IL-1F6),Interleukin-36 alpha

Target products collectionGo to IL-1F6/IL-36 Alpha/IL36A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1029-Ag-1/ GM-Tg-hg-SE1029-Ag-2 Human IL-1F6/IL-36 Alpha/IL36A protein Human
GM-Tg-rg-SE1029-Ag-1/ GM-Tg-rg-SE1029-Ag-2 Rat IL-1F6/IL-36 Alpha/IL36A protein Rat
GM-Tg-mg-SE1029-Ag-1/ GM-Tg-mg-SE1029-Ag-2 Mouse IL-1F6/IL-36 Alpha/IL36A protein Mouse
GM-Tg-cynog-SE1029-Ag-1/ GM-Tg-cynog-SE1029-Ag-2 Cynomolgus/Rhesus macaque IL-1F6/IL-36 Alpha/IL36A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1029-Ag-1/ GM-Tg-felg-SE1029-Ag-2 Feline IL-1F6/IL-36 Alpha/IL36A protein Feline
GM-Tg-cang-SE1029-Ag-1/ GM-Tg-cang-SE1029-Ag-2 Canine IL-1F6/IL-36 Alpha/IL36A protein Canine
GM-Tg-bovg-SE1029-Ag-1/ GM-Tg-bovg-SE1029-Ag-2 Bovine IL-1F6/IL-36 Alpha/IL36A protein Bovine
GM-Tg-equg-SE1029-Ag-1/ GM-Tg-equg-SE1029-Ag-2 Equine IL-1F6/IL-36 Alpha/IL36A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1029-Ag-1/ GM-Tg-hg-SE1029-Ag-2; GM-Tg-rg-SE1029-Ag-1/ GM-Tg-rg-SE1029-Ag-2;
GM-Tg-mg-SE1029-Ag-1/ GM-Tg-mg-SE1029-Ag-2; GM-Tg-cynog-SE1029-Ag-1/ GM-Tg-cynog-SE1029-Ag-2;
GM-Tg-felg-SE1029-Ag-1/ GM-Tg-felg-SE1029-Ag-2; GM-Tg-cang-SE1029-Ag-1/ GM-Tg-cang-SE1029-Ag-2;
GM-Tg-bovg-SE1029-Ag-1/ GM-Tg-bovg-SE1029-Ag-2; GM-Tg-equg-SE1029-Ag-1/ GM-Tg-equg-SE1029-Ag-2
Products Name IL-1F6/IL-36 Alpha/IL36A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IL-1F6/IL-36 Alpha/IL36A
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-1F6/IL-36 Alpha/IL36A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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