Explore BDNF gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]
| Target ID |
GM-T93122
|
| Target Name |
BDNF
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
627
|
| Gene ID |
100009689 (Equus caballus), 12064 (Mus musculus), 24225 (Rattus norvegicus), 403461 (Canis lupus familiaris)
493690 (Felis catus), 617701 (Bos taurus), 627 (Homo sapiens), 701245 (Macaca mulatta)
|
| Target Alternative Names |
ANON2,Abrineurin,BDNF,BULN2,Bdnf,Brain-derived neurotrophic factor,Neurotrophic factor BDNF precursor form,proBDNF
|
| Uniprot Accession |
Q0EAB7,P21237,P23363,Q7YRB4,Q9TST3,Q95106,P23560,Q06225
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Prostate Cancer, ovarian cancer, Overactive bladder, Autism, mental retardation, Allergic reactions, Asthma, Parkinson's Disease
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, cAMP signaling pathway, PI3K-Akt signaling pathway, Neurotrophin signaling pathway, Cocaine addiction
|
| Gene Ensembl |
ENSECAG00000015952, ENSMUSG00000048482, ENSBTAG00000008134, ENSG00000176697, ENSMMUG00000008634
|
Pre-made viral vector of BDNF cDNA Clones/ORF Plasmid
BDNF siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo627 | Pre-made Human BDNF/ANON2/BULN2 siRNA oligo Duplex | 627 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24225 | Pre-made Rat Bdnf siRNA oligo Duplex | 24225 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12064 | Pre-made Mouse Bdnf siRNA oligo Duplex | 12064 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701245 | Pre-made Cynomolgus/Rhesus macaque BDNF siRNA oligo Duplex | 701245 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493690 | Pre-made Cat/Feline BDNF siRNA oligo Duplex | 493690 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403461 | Pre-made Dog/Canine BDNF siRNA oligo Duplex | 403461 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo617701 | Pre-made Bovines/Cattle BDNF siRNA oligo Duplex | 617701 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009689 | Pre-made Equine/Horse BDNF siRNA oligo Duplex | 100009689 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BDNF antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T93122-Ab | Human | Anti-Human BDNF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T93122-Ab | Rat | Anti-Rat BDNF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T93122-Ab | Mouse | Anti-Mouse BDNF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T93122-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BDNF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T93122-Ab | Cat/Feline | Anti-Cat/Feline BDNF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T93122-Ab | Dog/Canine | Anti-Dog/Canine BDNF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T93122-Ab | Bovines/Cattle | Anti-Bovines/Cattle BDNF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T93122-Ab | Equine/Horse | Anti-Equine/Horse BDNF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
BDNF recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T93122-Ag | Human | Human BDNF recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T93122-Ag | Rat | Rat BDNF recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T93122-Ag | Mouse | Mouse BDNF recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T93122-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BDNF recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T93122-Ag | Cat/Feline | Cat/Feline BDNF recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T93122-Ag | Dog/Canine | Dog/Canine BDNF recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T93122-Ag | Bovines/Cattle | Bovines/Cattle BDNF recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T93122-Ag | Equine/Horse | Equine/Horse BDNF recombinant protein | Mammalian cell | Detail |
