Recombinant multi-species BDNF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BDNF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]
The Alternative Names of target: ANON2,Abrineurin,BDNF,BULN2,Bdnf,Brain-derived neurotrophic factor,Neurotrophic factor BDNF precursor form,proBDNF

Target products collectionGo to BDNF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T93122-Ag-1/ GM-Tg-hg-T93122-Ag-2 Human BDNF protein Human
GM-Tg-rg-T93122-Ag-1/ GM-Tg-rg-T93122-Ag-2 Rat BDNF protein Rat
GM-Tg-mg-T93122-Ag-1/ GM-Tg-mg-T93122-Ag-2 Mouse BDNF protein Mouse
GM-Tg-cynog-T93122-Ag-1/ GM-Tg-cynog-T93122-Ag-2 Cynomolgus/Rhesus macaque BDNF protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T93122-Ag-1/ GM-Tg-felg-T93122-Ag-2 Feline BDNF protein Feline
GM-Tg-cang-T93122-Ag-1/ GM-Tg-cang-T93122-Ag-2 Canine BDNF protein Canine
GM-Tg-bovg-T93122-Ag-1/ GM-Tg-bovg-T93122-Ag-2 Bovine BDNF protein Bovine
GM-Tg-equg-T93122-Ag-1/ GM-Tg-equg-T93122-Ag-2 Equine BDNF protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T93122-Ag-1/ GM-Tg-hg-T93122-Ag-2; GM-Tg-rg-T93122-Ag-1/ GM-Tg-rg-T93122-Ag-2;
GM-Tg-mg-T93122-Ag-1/ GM-Tg-mg-T93122-Ag-2; GM-Tg-cynog-T93122-Ag-1/ GM-Tg-cynog-T93122-Ag-2;
GM-Tg-felg-T93122-Ag-1/ GM-Tg-felg-T93122-Ag-2; GM-Tg-cang-T93122-Ag-1/ GM-Tg-cang-T93122-Ag-2;
GM-Tg-bovg-T93122-Ag-1/ GM-Tg-bovg-T93122-Ag-2; GM-Tg-equg-T93122-Ag-1/ GM-Tg-equg-T93122-Ag-2
Products Name BDNF protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name BDNF
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BDNF protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.