PDGF-BB/PDGFB/PDGFBB Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore PDGF-BB/PDGFB/PDGFBB gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Pre-made viral vector of PDGF-BB/PDGFB/PDGFBB cDNA Clones/ORF Plasmid

PDGF-BB/PDGFB/PDGFBB siRNA/miRNA/oligo for RNA interfence (RNAi)

PDGF-BB/PDGFB/PDGFBB antibody/GMab

PDGF-BB/PDGFB/PDGFBB recombinant protein