Recombinant multi-species PDGF-BB/PDGFB/PDGFBB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDGF-BB/PDGFB/PDGFBB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
The Alternative Names of target: IBGC5,PDGF,PDGF subunit B,PDGF-2,PDGF-B,PDGF-BB,PDGF2,PDGFB,PDGFBB,Pdgfb,Platelet-derived growth factor B chain,Platelet-derived growth factor beta polypeptide,Platelet-derived growth factor subunit B,Proto-oncogene c-Sis,SIS,SSV,Sis,c-sis,cis

Target products collectionGo to PDGF-BB/PDGFB/PDGFBB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T87350-Ag-1/ GM-Tg-hg-T87350-Ag-2 Human PDGF-BB/PDGFB/PDGFBB protein Human
GM-Tg-rg-T87350-Ag-1/ GM-Tg-rg-T87350-Ag-2 Rat PDGF-BB/PDGFB/PDGFBB protein Rat
GM-Tg-mg-T87350-Ag-1/ GM-Tg-mg-T87350-Ag-2 Mouse PDGF-BB/PDGFB/PDGFBB protein Mouse
GM-Tg-cynog-T87350-Ag-1/ GM-Tg-cynog-T87350-Ag-2 Cynomolgus/Rhesus macaque PDGF-BB/PDGFB/PDGFBB protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T87350-Ag-1/ GM-Tg-felg-T87350-Ag-2 Feline PDGF-BB/PDGFB/PDGFBB protein Feline
GM-Tg-cang-T87350-Ag-1/ GM-Tg-cang-T87350-Ag-2 Canine PDGF-BB/PDGFB/PDGFBB protein Canine
GM-Tg-bovg-T87350-Ag-1/ GM-Tg-bovg-T87350-Ag-2 Bovine PDGF-BB/PDGFB/PDGFBB protein Bovine
GM-Tg-equg-T87350-Ag-1/ GM-Tg-equg-T87350-Ag-2 Equine PDGF-BB/PDGFB/PDGFBB protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T87350-Ag-1/ GM-Tg-hg-T87350-Ag-2; GM-Tg-rg-T87350-Ag-1/ GM-Tg-rg-T87350-Ag-2;
GM-Tg-mg-T87350-Ag-1/ GM-Tg-mg-T87350-Ag-2; GM-Tg-cynog-T87350-Ag-1/ GM-Tg-cynog-T87350-Ag-2;
GM-Tg-felg-T87350-Ag-1/ GM-Tg-felg-T87350-Ag-2; GM-Tg-cang-T87350-Ag-1/ GM-Tg-cang-T87350-Ag-2;
GM-Tg-bovg-T87350-Ag-1/ GM-Tg-bovg-T87350-Ag-2; GM-Tg-equg-T87350-Ag-1/ GM-Tg-equg-T87350-Ag-2
Products Name PDGF-BB/PDGFB/PDGFBB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PDGF-BB/PDGFB/PDGFBB
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDGF-BB/PDGFB/PDGFBB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.