VHL Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore VHL gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a component of a ubiquitination complex. The encoded protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. In addition to oxygen-related gene expression, this protein plays a role in many other cellular processes including cilia formation, cytokine signaling, regulation of senescence, and formation of the extracellular matrix. Variants of this gene are associated with von Hippel-Lindau syndrome, pheochromocytoma, erythrocytosis, renal cell carcinoma, and cerebellar hemangioblastoma. [provided by RefSeq, Jun 2022]

Target ID GM-T80423
Target Name VHL
Gene Group ldentifer
（Target Gene ID in Homo species) 		7428
Gene ID 100058139 (Equus caballus), 101092590 (Felis catus), 106996285 (Macaca mulatta), 22346 (Mus musculus)
24874 (Rattus norvegicus), 494000 (Canis lupus familiaris), 540957 (Bos taurus), 7428 (Homo sapiens)
Target Alternative Names HRCA1,Protein G7,RCA1,VHL,VHL1,Vhl,Vhlh,pVHL,von Hippel-Lindau disease tumor suppressor
Uniprot Accession P40338,Q64259,Q5Q9Z2,P40337
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG HIF-1 signaling pathway, Pathways in cancer, Renal cell carcinoma
Gene Ensembl ENSMMUG00000056789, ENSMUSG00000033933, ENSCAFG00845008162, ENSG00000134086
Target Classification Tumor-associated antigen (TAA)


Pre-made viral vector of VHL cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP000945Human VHL/HRCA1/pVHL Lentivirus plasmidNM_0005517428HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC000615Human VHL/HRCA1/pVHL Mammalian (Non-Viral Vector) plasmidNM_000551.47428HumanMammalian (Non-Viral Vector) plasmidZsGreenNullCMVDetail
vGMLP000945Human VHL/HRCA1/pVHL Lentivirus particleNM_0005517428HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV001591Rat Vhl/Vhlh Adeno-associate virus(AAV) plasmidNM_052801.224874RatAdeno-associate virus(AAV) plasmidEGFP3xflag (C-Terminal)CTNTDetail
vGMAAV001591Rat Vhl/Vhlh Adeno-associate virus(AAV) particleNM_052801.224874RatAdeno-associate virus(AAV) particleEGFP3xflag (C-Terminal)CTNTDetail
pGMLV002686Mouse Vhl/pVHL/Vhlh Lentivirus plasmidNM_009507.422346MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLPm000238Mouse Vhl/Vhlh Lentivirus plasmidNM_00950722346MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLV002686Mouse Vhl/pVHL/Vhlh Lentivirus particleNM_009507.422346MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm000238Mouse Vhl/Vhlh Lentivirus particleNM_00950722346MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


VHL siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo7428Pre-made Human VHL/RCA1/VHL1 siRNA oligo Duplex7428HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo24874Pre-made Rat Vhl/Vhlh siRNA oligo Duplex24874RatIn-vitro grade; in-vivo gradeDetail
pGMoligo22346Pre-made Mouse Vhl/Vhlh/pVHL siRNA oligo Duplex22346MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo106996285Pre-made Cynomolgus/Rhesus macaque VHL/pVHL siRNA oligo Duplex106996285Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101092590Pre-made Cat/Feline VHL siRNA oligo Duplex101092590Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo494000Pre-made Dog/Canine VHL siRNA oligo Duplex494000Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo540957Pre-made Bovines/Cattle VHL siRNA oligo Duplex540957Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100058139Pre-made Equine/Horse VHL siRNA oligo Duplex100058139Equine/HorseIn-vitro grade; in-vivo gradeDetail


VHL antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T80423-AbHumanAnti-Human VHL monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T80423-AbRatAnti-Rat VHL monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T80423-AbMouseAnti-Mouse VHL monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T80423-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque VHL monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T80423-AbCat/FelineAnti-Cat/Feline VHL monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T80423-AbDog/CanineAnti-Dog/Canine VHL monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T80423-AbBovines/CattleAnti-Bovines/Cattle VHL monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T80423-AbEquine/HorseAnti-Equine/Horse VHL monoclonal antibodymabTherapeutics Target antibodyDetail


VHL recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T80423-AgHumanHuman VHL recombinant proteinMammalian cellDetail
GM-Tg-rg-T80423-AgRatRat VHL recombinant proteinMammalian cellDetail
GM-Tg-mg-T80423-AgMouseMouse VHL recombinant proteinMammalian cellDetail
GM-Tg-cynog-T80423-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque VHL recombinant proteinMammalian cellDetail
GM-Tg-felg-T80423-AgCat/FelineCat/Feline VHL recombinant proteinMammalian cellDetail
GM-Tg-cang-T80423-AgDog/CanineDog/Canine VHL recombinant proteinMammalian cellDetail
GM-Tg-bovg-T80423-AgBovines/CattleBovines/Cattle VHL recombinant proteinMammalian cellDetail
GM-Tg-equg-T80423-AgEquine/HorseEquine/Horse VHL recombinant proteinMammalian cellDetail