Human VHL/HRCA1/pVHL ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_000551.4)

Cat. No.: pGMPC000615
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human VHL/HRCA1/pVHL Non-Viral expression plasmid (overexpression vector) for mouse VHL overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000615
Gene Name VHL
Accession Number NM_000551.4
Gene ID 7428
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 642 bp
Gene Alias HRCA1,pVHL,RCA1,VHL1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag Null
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCCCCGGAGGGCGGAGAACTGGGACGAGGCCGAGGTAGGCGCGGAGGAGGCAGGCGTCGAAGAGTACGGCCCTGAAGAAGACGGCGGGGAGGAGTCGGGCGCCGAGGAGTCCGGCCCGGAAGAGTCCGGCCCGGAGGAACTGGGCGCCGAGGAGGAGATGGAGGCCGGGCGGCCGCGGCCCGTGCTGCGCTCGGTGAACTCGCGCGAGCCCTCCCAGGTCATCTTCTGCAATCGCAGTCCGCGCGTCGTGCTGCCCGTATGGCTCAACTTCGACGGCGAGCCGCAGCCCTACCCAACGCTGCCGCCTGGCACGGGCCGCCGCATCCACAGCTACCGAGGTCACCTTTGGCTCTTCAGAGATGCAGGGACACACGATGGGCTTCTGGTTAACCAAACTGAATTATTTGTGCCATCTCTCAATGTTGACGGACAGCCTATTTTTGCCAATATCACACTGCCAGTGTATACTCTGAAAGAGCGATGCCTCCAGGTTGTCCGGAGCCTAGTCAAGCCTGAGAATTACAGGAGACTGGACATCGTCAGGTCGCTCTACGAAGATCTGGAAGACCACCCAAATGTGCAGAAAGACCTGGAGCGGCTGACACAGGAGCGCATTGCACATCAACGGATGGGAGATTGA
ORF Protein Sequence MPRRAENWDEAEVGAEEAGVEEYGPEEDGGEESGAEESGPEESGPEELGAEEEMEAGRPRPVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAHQRMGD

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T80423-Ab Anti-VHL monoclonal antibody
    Target Antigen GM-Tg-g-T80423-Ag VHL protein
    ORF Viral Vector pGMLP000945 Human VHL Lentivirus plasmid
    ORF Viral Vector pGMPC000615 Human VHL Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP000945 Human VHL Lentivirus particle


    Target information

    Target ID GM-T80423
    Target Name VHL
    Gene Group Identifier
    （Target Gene ID in Homo species)         		7428
    Gene ID 100058139 (Equus caballus), 101092590 (Felis catus), 106996285 (Macaca mulatta), 22346 (Mus musculus)
    24874 (Rattus norvegicus), 494000 (Canis lupus familiaris), 540957 (Bos taurus), 7428 (Homo sapiens)
    Gene Symbols & Synonyms VHL,Vhl,pVHL,Vhlh,RCA1,VHL1,HRCA1
    Target Alternative Names HRCA1,Protein G7,RCA1,VHL,VHL1,Vhl,Vhlh,pVHL,von Hippel-Lindau disease tumor suppressor
    Uniprot Accession P40337,P40338,Q5Q9Z2,Q64259
    Additional SwissProt Accessions: P40338,Q64259,Q5Q9Z2,P40337
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG HIF-1 signaling pathway, Pathways in cancer, Renal cell carcinoma
    Gene Ensembl ENSMMUG00000056789, ENSMUSG00000033933, ENSCAFG00845008162, ENSG00000134086
    Target Classification Tumor-associated antigen (TAA)


    About GMVC

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