Explore IFN-gamma/IFNG gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
Target ID |
GM-T77664
|
Target Name |
IFN-gamma/IFNG
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3458
|
Gene ID |
100034181 (Equus caballus), 15978 (Mus musculus), 25712 (Rattus norvegicus), 281237 (Bos taurus) 3458 (Homo sapiens), 403801 (Canis lupus familiaris), 493965 (Felis catus), 574282 (Macaca mulatta)
|
Target Alternative Names |
IFNG,Ifng,IF2F,Ifg,If2f,IFN-g,IFNG2,IFG,IFI,IMD69,IFN-G,IFN-gamma
|
Uniprot Accession |
P42160,P01580,P01581,P07353,P01579,P42161,P46402,P63310
|
Uniprot Entry Name |
|
Protein Sub-location |
Secreted Protein/Potential Cytokines
|
Category |
Therapeutics Target, Diagnostics Biomarker, Immuno-oncology Target, INN Index, Cytokine Target
|
Disease |
cancer, Breast Cancer
|
Disease from KEGG |
Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Type I diabetes mellitus, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Influenza A, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Inflammatory bowel disease, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Fluid shear stress and atherosclerosis
|
Gene Ensembl |
ENSECAG00000028288, ENSMUSG00000055170, ENSBTAG00000012529, ENSG00000111537, ENSCAFG00845013680, ENSMMUG00000056408
|
Target Classification |
Cytokine Receptor, Checkpoint-Immuno Oncology
|
Pre-made viral vector of IFN-gamma/IFNG cDNA Clones/ORF Plasmid
IFN-gamma/IFNG siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo3458 | Pre-made Human IFNG/IFG/IFI siRNA oligo Duplex | 3458 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo25712 | Pre-made Rat Ifng/If2f/IFNG2 siRNA oligo Duplex | 25712 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo15978 | Pre-made Mouse Ifng/Ifg/If2f siRNA oligo Duplex | 15978 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo574282 | Pre-made Cynomolgus/Rhesus macaque IFNG/IFN-gamma siRNA oligo Duplex | 574282 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo493965 | Pre-made Cat/Feline IFNG siRNA oligo Duplex | 493965 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo403801 | Pre-made Dog/Canine IFNG/IFN-G/IFN-gamma siRNA oligo Duplex | 403801 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo281237 | Pre-made Bovines/Cattle IFNG siRNA oligo Duplex | 281237 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100034181 | Pre-made Equine/Horse IFNG/IF2F siRNA oligo Duplex | 100034181 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IFN-gamma/IFNG antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T77664-Ab | Human | Anti-Human IFN-gamma/IFNG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
GM-Tg-rg-T77664-Ab | Rat | Anti-Rat IFN-gamma/IFNG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
GM-Tg-mg-T77664-Ab | Mouse | Anti-Mouse IFN-gamma/IFNG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
GM-Tg-cynog-T77664-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IFN-gamma/IFNG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
GM-Tg-felg-T77664-Ab | Cat/Feline | Anti-Cat/Feline IFN-gamma/IFNG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
GM-Tg-cang-T77664-Ab | Dog/Canine | Anti-Dog/Canine IFN-gamma/IFNG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
GM-Tg-bovg-T77664-Ab | Bovines/Cattle | Anti-Bovines/Cattle IFN-gamma/IFNG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
GM-Tg-equg-T77664-Ab | Equine/Horse | Anti-Equine/Horse IFN-gamma/IFNG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
IFN-gamma/IFNG recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T77664-Ag | Human | Human IFN-gamma/IFNG recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-T77664-Ag | Rat | Rat IFN-gamma/IFNG recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-T77664-Ag | Mouse | Mouse IFN-gamma/IFNG recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-T77664-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IFN-gamma/IFNG recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-T77664-Ag | Cat/Feline | Cat/Feline IFN-gamma/IFNG recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-T77664-Ag | Dog/Canine | Dog/Canine IFN-gamma/IFNG recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-T77664-Ag | Bovines/Cattle | Bovines/Cattle IFN-gamma/IFNG recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-T77664-Ag | Equine/Horse | Equine/Horse IFN-gamma/IFNG recombinant protein | Mammalian cell | Detail |