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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]
| Target ID |
GM-T73475
|
| Target Name |
MMP7/MMP-7
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4316
|
| Gene ID |
100068985 (Equus caballus), 17393 (Mus musculus), 25335 (Rattus norvegicus), 286794 (Bos taurus) 4316 (Homo sapiens), 489432 (Canis lupus familiaris), 703072 (Macaca mulatta), 727698 (Felis catus)
|
| Target Alternative Names |
MAT,MMP-7,MMP7,MPMM,MPSL1,Matrilysin,Matrin,Matrix metalloproteinase-7 (MMP-7),Mmp7,PUMP-1,Pump-1 protease,Uterine metalloproteinase
|
| Uniprot Accession |
Q10738,P50280,P09237,P55032
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Ovary Cancer, Chronic Kidney Disease
|
| Disease from KEGG |
Wnt signaling pathway, Human T-cell leukemia virus 1 infection
|
| Gene Ensembl |
ENSECAG00000021262, ENSMUSG00000018623, ENSBTAG00000004594, ENSG00000137673, ENSCAFG00845000992, ENSMMUG00000003405
|
Pre-made viral vector of MMP7/MMP-7 cDNA Clones/ORF Plasmid
MMP7/MMP-7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4316 | Pre-made Human MMP7/MMP-7/MPSL1 siRNA oligo Duplex | 4316 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25335 | Pre-made Rat Mmp7/MPMM siRNA oligo Duplex | 25335 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17393 | Pre-made Mouse Mmp7/MAT/MMP-7 siRNA oligo Duplex | 17393 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703072 | Pre-made Cynomolgus/Rhesus macaque MMP7 siRNA oligo Duplex | 703072 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo727698 | Pre-made Cat/Feline MMP7/Matrilysin siRNA oligo Duplex | 727698 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489432 | Pre-made Dog/Canine MMP7 siRNA oligo Duplex | 489432 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo286794 | Pre-made Bovines/Cattle MMP7 siRNA oligo Duplex | 286794 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068985 | Pre-made Equine/Horse MMP7 siRNA oligo Duplex | 100068985 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MMP7/MMP-7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T73475-Ab | Human | Anti-Human MMP7/MMP-7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T73475-Ab | Rat | Anti-Rat MMP7/MMP-7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T73475-Ab | Mouse | Anti-Mouse MMP7/MMP-7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T73475-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MMP7/MMP-7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T73475-Ab | Cat/Feline | Anti-Cat/Feline MMP7/MMP-7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T73475-Ab | Dog/Canine | Anti-Dog/Canine MMP7/MMP-7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T73475-Ab | Bovines/Cattle | Anti-Bovines/Cattle MMP7/MMP-7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T73475-Ab | Equine/Horse | Anti-Equine/Horse MMP7/MMP-7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MMP7/MMP-7 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T73475-Ag | Human | Human MMP7/MMP-7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T73475-Ag | Rat | Rat MMP7/MMP-7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T73475-Ag | Mouse | Mouse MMP7/MMP-7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T73475-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MMP7/MMP-7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T73475-Ag | Cat/Feline | Cat/Feline MMP7/MMP-7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T73475-Ag | Dog/Canine | Dog/Canine MMP7/MMP-7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T73475-Ag | Bovines/Cattle | Bovines/Cattle MMP7/MMP-7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T73475-Ag | Equine/Horse | Equine/Horse MMP7/MMP-7 recombinant protein | Mammalian cell | Detail |