Recombinant multi-species MMP7/MMP-7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMP7/MMP-7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]
The Alternative Names of target: MAT,MMP-7,MMP7,MPMM,MPSL1,Matrilysin,Matrin,Matrix metalloproteinase-7 (MMP-7),Mmp7,PUMP-1,Pump-1 protease,Uterine metalloproteinase

Target products collectionGo to MMP7/MMP-7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T73475-Ag-1/ GM-Tg-hg-T73475-Ag-2 Human MMP7/MMP-7 protein Human
GM-Tg-rg-T73475-Ag-1/ GM-Tg-rg-T73475-Ag-2 Rat MMP7/MMP-7 protein Rat
GM-Tg-mg-T73475-Ag-1/ GM-Tg-mg-T73475-Ag-2 Mouse MMP7/MMP-7 protein Mouse
GM-Tg-cynog-T73475-Ag-1/ GM-Tg-cynog-T73475-Ag-2 Cynomolgus/Rhesus macaque MMP7/MMP-7 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T73475-Ag-1/ GM-Tg-felg-T73475-Ag-2 Feline MMP7/MMP-7 protein Feline
GM-Tg-cang-T73475-Ag-1/ GM-Tg-cang-T73475-Ag-2 Canine MMP7/MMP-7 protein Canine
GM-Tg-bovg-T73475-Ag-1/ GM-Tg-bovg-T73475-Ag-2 Bovine MMP7/MMP-7 protein Bovine
GM-Tg-equg-T73475-Ag-1/ GM-Tg-equg-T73475-Ag-2 Equine MMP7/MMP-7 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T73475-Ag-1/ GM-Tg-hg-T73475-Ag-2; GM-Tg-rg-T73475-Ag-1/ GM-Tg-rg-T73475-Ag-2;
GM-Tg-mg-T73475-Ag-1/ GM-Tg-mg-T73475-Ag-2; GM-Tg-cynog-T73475-Ag-1/ GM-Tg-cynog-T73475-Ag-2;
GM-Tg-felg-T73475-Ag-1/ GM-Tg-felg-T73475-Ag-2; GM-Tg-cang-T73475-Ag-1/ GM-Tg-cang-T73475-Ag-2;
GM-Tg-bovg-T73475-Ag-1/ GM-Tg-bovg-T73475-Ag-2; GM-Tg-equg-T73475-Ag-1/ GM-Tg-equg-T73475-Ag-2
Products Name MMP7/MMP-7 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MMP7/MMP-7
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMP7/MMP-7 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.