Explore IGF1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]
| Target ID |
GM-T60930
|
| Target Name |
IGF1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3479
|
| Gene ID |
100034198 (Equus caballus), 101101237 (Felis catus), 16000 (Mus musculus), 24482 (Rattus norvegicus)
281239 (Bos taurus), 3479 (Homo sapiens), 610255 (Canis lupus familiaris), 698444 (Macaca mulatta)
|
| Target Alternative Names |
C730016P09Rik,IGF,IGF-1,IGF-I,IGF1,IGFI,IGFIA,Igf-1,Igf-I,Igf1,Insulin-like growth factor 1,Insulin-like growth factor I (IGF-I),MGF,Mechano growth factor (MGF),Somatomedin-C
|
| Uniprot Accession |
P51458,P05017,P08025,P07455,P05019,P33712
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, INN Index, Cytokine Target
|
| Disease |
cancer, Prostate Cancer
|
| Disease from KEGG |
EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, p53 signaling pathway, PI3K-Akt signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Focal adhesion, Signaling pathways regulating pluripotency of stem cells, Inflammatory mediator regulation of TRP channels, Ovarian steroidogenesis, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Pathways in cancer, Proteoglycans in cancer, Glioma, Prostate cancer, Melanoma, Breast cancer, Hypertrophic cardiomyopathy, Dilated cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000010109, ENSMUSG00000020053, ENSBTAG00000011082, ENSG00000017427, ENSCAFG00845009366, ENSMMUG00000002235
|
Pre-made viral vector of IGF1 cDNA Clones/ORF Plasmid
IGF1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3479 | Pre-made Human IGF1/IGF/MGF siRNA oligo Duplex | 3479 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24482 | Pre-made Rat Igf1/IGF siRNA oligo Duplex | 24482 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16000 | Pre-made Mouse Igf1/Igf-1/Igf-I siRNA oligo Duplex | 16000 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698444 | Pre-made Cynomolgus/Rhesus macaque IGF1 siRNA oligo Duplex | 698444 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101237 | Pre-made Cat/Feline IGF1 siRNA oligo Duplex | 101101237 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610255 | Pre-made Dog/Canine IGF1/IGFI/IGF-I siRNA oligo Duplex | 610255 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281239 | Pre-made Bovines/Cattle IGF1/IGF-1/IGF-I siRNA oligo Duplex | 281239 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034198 | Pre-made Equine/Horse IGF1 siRNA oligo Duplex | 100034198 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IGF1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T60930-Ab | Human | Anti-Human IGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T60930-Ab | Rat | Anti-Rat IGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T60930-Ab | Mouse | Anti-Mouse IGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T60930-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T60930-Ab | Cat/Feline | Anti-Cat/Feline IGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T60930-Ab | Dog/Canine | Anti-Dog/Canine IGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T60930-Ab | Bovines/Cattle | Anti-Bovines/Cattle IGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T60930-Ab | Equine/Horse | Anti-Equine/Horse IGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IGF1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T60930-Ag | Human | Human IGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T60930-Ag | Rat | Rat IGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T60930-Ag | Mouse | Mouse IGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T60930-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T60930-Ag | Cat/Feline | Cat/Feline IGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T60930-Ag | Dog/Canine | Dog/Canine IGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T60930-Ag | Bovines/Cattle | Bovines/Cattle IGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T60930-Ag | Equine/Horse | Equine/Horse IGF1 recombinant protein | Mammalian cell | Detail |
