Explore Cyclophilin A/PPIA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T47081
|
| Target Name |
Cyclophilin A/PPIA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5478
|
| Gene ID |
100052020 (Equus caballus), 25518 (Rattus norvegicus), 268373 (Mus musculus), 281418 (Bos taurus)
493966 (Felis catus), 5478 (Homo sapiens), 574102 (Macaca mulatta), 608151 (Canis lupus familiaris)
|
| Target Alternative Names |
CYCA,CYPA,CYPH,Cphn,CyP-18,CyP-A,Cyclophilin A,Cyclosporin A-binding protein,CypA,HEL-S-69p,MT-ND1,MTND1,NADH1,ND1,PPIA,PPIase A,Peptidyl-prolyl cis-trans isomerase A,Ppia,Rotamase A,SP18,cypA,p1B15,p31
|
| Uniprot Accession |
P10111,P17742,P62935,P48900,Q8HXS3,P62937,P62940
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000016673, ENSMUSG00000071866, ENSBTAG00000012003, ENSG00000196262, ENSMMUG00000016638
|
Pre-made viral vector of Cyclophilin A/PPIA cDNA Clones/ORF Plasmid
Cyclophilin A/PPIA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5478 | Pre-made Human PPIA/CYPA/CYPH siRNA oligo Duplex | 5478 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25518 | Pre-made Rat Ppia/p31/CYCA siRNA oligo Duplex | 25518 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo268373 | Pre-made Mouse Ppia/Cphn/CypA siRNA oligo Duplex | 268373 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574102 | Pre-made Cynomolgus/Rhesus macaque PPIA/CYPA siRNA oligo Duplex | 574102 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493966 | Pre-made Cat/Feline PPIA/ND1/cypA siRNA oligo Duplex | 493966 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608151 | Pre-made Dog/Canine PPIA siRNA oligo Duplex | 608151 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281418 | Pre-made Bovines/Cattle PPIA siRNA oligo Duplex | 281418 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052020 | Pre-made Equine/Horse PPIA siRNA oligo Duplex | 100052020 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Cyclophilin A/PPIA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T47081-Ab | Human | Anti-Human Cyclophilin A/PPIA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T47081-Ab | Rat | Anti-Rat Cyclophilin A/PPIA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T47081-Ab | Mouse | Anti-Mouse Cyclophilin A/PPIA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T47081-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Cyclophilin A/PPIA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T47081-Ab | Cat/Feline | Anti-Cat/Feline Cyclophilin A/PPIA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T47081-Ab | Dog/Canine | Anti-Dog/Canine Cyclophilin A/PPIA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T47081-Ab | Bovines/Cattle | Anti-Bovines/Cattle Cyclophilin A/PPIA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T47081-Ab | Equine/Horse | Anti-Equine/Horse Cyclophilin A/PPIA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Cyclophilin A/PPIA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T47081-Ag | Human | Human Cyclophilin A/PPIA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T47081-Ag | Rat | Rat Cyclophilin A/PPIA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T47081-Ag | Mouse | Mouse Cyclophilin A/PPIA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T47081-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Cyclophilin A/PPIA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T47081-Ag | Cat/Feline | Cat/Feline Cyclophilin A/PPIA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T47081-Ag | Dog/Canine | Dog/Canine Cyclophilin A/PPIA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T47081-Ag | Bovines/Cattle | Bovines/Cattle Cyclophilin A/PPIA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T47081-Ag | Equine/Horse | Equine/Horse Cyclophilin A/PPIA recombinant protein | Mammalian cell | Detail |
