Recombinant multi-species Cyclophilin A/PPIA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cyclophilin A/PPIA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CYCA,CYPA,CYPH,Cphn,CyP-18,CyP-A,Cyclophilin A,Cyclosporin A-binding protein,CypA,HEL-S-69p,MT-ND1,MTND1,NADH1,ND1,PPIA,PPIase A,Peptidyl-prolyl cis-trans isomerase A,Ppia,Rotamase A,SP18,cypA,p1B15,p31
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T47081-Ag-1/ GM-Tg-hg-T47081-Ag-2 | Human Cyclophilin A/PPIA protein | Human |
| GM-Tg-rg-T47081-Ag-1/ GM-Tg-rg-T47081-Ag-2 | Rat Cyclophilin A/PPIA protein | Rat |
| GM-Tg-mg-T47081-Ag-1/ GM-Tg-mg-T47081-Ag-2 | Mouse Cyclophilin A/PPIA protein | Mouse |
| GM-Tg-cynog-T47081-Ag-1/ GM-Tg-cynog-T47081-Ag-2 | Cynomolgus/Rhesus macaque Cyclophilin A/PPIA protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T47081-Ag-1/ GM-Tg-felg-T47081-Ag-2 | Feline Cyclophilin A/PPIA protein | Feline |
| GM-Tg-cang-T47081-Ag-1/ GM-Tg-cang-T47081-Ag-2 | Canine Cyclophilin A/PPIA protein | Canine |
| GM-Tg-bovg-T47081-Ag-1/ GM-Tg-bovg-T47081-Ag-2 | Bovine Cyclophilin A/PPIA protein | Bovine |
| GM-Tg-equg-T47081-Ag-1/ GM-Tg-equg-T47081-Ag-2 | Equine Cyclophilin A/PPIA protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T47081-Ag-1/ GM-Tg-hg-T47081-Ag-2;
GM-Tg-rg-T47081-Ag-1/ GM-Tg-rg-T47081-Ag-2;
GM-Tg-mg-T47081-Ag-1/ GM-Tg-mg-T47081-Ag-2; GM-Tg-cynog-T47081-Ag-1/ GM-Tg-cynog-T47081-Ag-2; GM-Tg-felg-T47081-Ag-1/ GM-Tg-felg-T47081-Ag-2; GM-Tg-cang-T47081-Ag-1/ GM-Tg-cang-T47081-Ag-2; GM-Tg-bovg-T47081-Ag-1/ GM-Tg-bovg-T47081-Ag-2; GM-Tg-equg-T47081-Ag-1/ GM-Tg-equg-T47081-Ag-2 |
| Products Name | Cyclophilin A/PPIA protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | Cyclophilin A/PPIA |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cyclophilin A/PPIA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
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capabilities of GM’s Taurus™ and LIBRA™
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characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.