Explore c-Fos/FOS gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T28025
|
| Target Name |
c-Fos/FOS
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2353
|
| Gene ID |
100051632 (Equus caballus), 14281 (Mus musculus), 2353 (Homo sapiens), 280795 (Bos taurus) 314322 (Rattus norvegicus), 490792 (Canis lupus familiaris), 493935 (Felis catus), 702077 (Macaca mulatta)
|
| Target Alternative Names |
AP-1,AP-1 transcription factor subunit,C-FOS,Cellular oncogene fos,D12Rfj1,FOS,Fos,Fos proto-oncogene,G0/G1 switch regulatory protein 7,Protein c-Fos,Proto-oncogene c-Fos,Transcription factor AP-1 subunit c-Fos,c-Fos,c-fos,cFos,p55
|
| Uniprot Accession |
P01101,P01100,O77628,P12841,Q8HZP6
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Endocrine resistance, MAPK signaling pathway, cAMP signaling pathway, Apoptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, IL-17 signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, TNF signaling pathway, Circadian entrainment, Cholinergic synapse, Prolactin signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Growth hormone synthesis, secretion and action, Amphetamine addiction, Pathogenic Escherichia coli infection, Pertussis, Yersinia infection, Leishmaniasis, Chagas disease, Hepatitis B, Measles, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer, Breast cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Rheumatoid arthritis, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000014260, ENSMUSG00000021250, ENSG00000170345, ENSBTAG00000004322, ENSCAFG00845015304, ENSMMUG00000040100
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of c-Fos/FOS cDNA Clones/ORF Plasmid
c-Fos/FOS siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2353 | Pre-made Human FOS/p55/AP-1 siRNA oligo Duplex | 2353 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo314322 | Pre-made Rat Fos/c-fos siRNA oligo Duplex | 314322 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14281 | Pre-made Mouse Fos/cFos/c-fos siRNA oligo Duplex | 14281 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702077 | Pre-made Cynomolgus/Rhesus macaque FOS/c-fos siRNA oligo Duplex | 702077 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493935 | Pre-made Cat/Feline FOS/c-fos siRNA oligo Duplex | 493935 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490792 | Pre-made Dog/Canine FOS siRNA oligo Duplex | 490792 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280795 | Pre-made Bovines/Cattle FOS siRNA oligo Duplex | 280795 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051632 | Pre-made Equine/Horse FOS siRNA oligo Duplex | 100051632 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
c-Fos/FOS antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T28025-Ab | Human | Anti-Human c-Fos/FOS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T28025-Ab | Rat | Anti-Rat c-Fos/FOS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T28025-Ab | Mouse | Anti-Mouse c-Fos/FOS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T28025-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque c-Fos/FOS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T28025-Ab | Cat/Feline | Anti-Cat/Feline c-Fos/FOS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T28025-Ab | Dog/Canine | Anti-Dog/Canine c-Fos/FOS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T28025-Ab | Bovines/Cattle | Anti-Bovines/Cattle c-Fos/FOS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T28025-Ab | Equine/Horse | Anti-Equine/Horse c-Fos/FOS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
c-Fos/FOS recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T28025-Ag | Human | Human c-Fos/FOS recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T28025-Ag | Rat | Rat c-Fos/FOS recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T28025-Ag | Mouse | Mouse c-Fos/FOS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T28025-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque c-Fos/FOS recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T28025-Ag | Cat/Feline | Cat/Feline c-Fos/FOS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T28025-Ag | Dog/Canine | Dog/Canine c-Fos/FOS recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T28025-Ag | Bovines/Cattle | Bovines/Cattle c-Fos/FOS recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T28025-Ag | Equine/Horse | Equine/Horse c-Fos/FOS recombinant protein | Mammalian cell | Detail |