Recombinant multi-species c-Fos/FOS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine c-Fos/FOS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2.  These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1.  As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.  In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]
The Alternative Names of target: AP-1,AP-1 transcription factor subunit,C-FOS,Cellular oncogene fos,D12Rfj1,FOS,Fos,Fos proto-oncogene,G0/G1 switch regulatory protein 7,Protein c-Fos,Proto-oncogene c-Fos,Transcription factor AP-1 subunit c-Fos,c-Fos,c-fos,cFos,p55

Target products collectionGo to c-Fos/FOS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T28025-Ag-1/ GM-Tg-hg-T28025-Ag-2 Human c-Fos/FOS protein Human
GM-Tg-rg-T28025-Ag-1/ GM-Tg-rg-T28025-Ag-2 Rat c-Fos/FOS protein Rat
GM-Tg-mg-T28025-Ag-1/ GM-Tg-mg-T28025-Ag-2 Mouse c-Fos/FOS protein Mouse
GM-Tg-cynog-T28025-Ag-1/ GM-Tg-cynog-T28025-Ag-2 Cynomolgus/Rhesus macaque c-Fos/FOS protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T28025-Ag-1/ GM-Tg-felg-T28025-Ag-2 Feline c-Fos/FOS protein Feline
GM-Tg-cang-T28025-Ag-1/ GM-Tg-cang-T28025-Ag-2 Canine c-Fos/FOS protein Canine
GM-Tg-bovg-T28025-Ag-1/ GM-Tg-bovg-T28025-Ag-2 Bovine c-Fos/FOS protein Bovine
GM-Tg-equg-T28025-Ag-1/ GM-Tg-equg-T28025-Ag-2 Equine c-Fos/FOS protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T28025-Ag-1/ GM-Tg-hg-T28025-Ag-2; GM-Tg-rg-T28025-Ag-1/ GM-Tg-rg-T28025-Ag-2;
GM-Tg-mg-T28025-Ag-1/ GM-Tg-mg-T28025-Ag-2; GM-Tg-cynog-T28025-Ag-1/ GM-Tg-cynog-T28025-Ag-2;
GM-Tg-felg-T28025-Ag-1/ GM-Tg-felg-T28025-Ag-2; GM-Tg-cang-T28025-Ag-1/ GM-Tg-cang-T28025-Ag-2;
GM-Tg-bovg-T28025-Ag-1/ GM-Tg-bovg-T28025-Ag-2; GM-Tg-equg-T28025-Ag-1/ GM-Tg-equg-T28025-Ag-2
Products Name c-Fos/FOS protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name c-Fos/FOS
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine c-Fos/FOS protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.