PPP3CA Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore PPP3CA gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
Enables several functions, including ATPase binding activity; calmodulin binding activity; and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; peptidyl-serine dephosphorylation; and response to calcium ion. Located in several cellular components, including cytosol; dendritic spine; and nucleoplasm. Part of calcineurin complex. Colocalizes with cytoplasmic side of plasma membrane. Implicated in developmental and epileptic encephalopathy 91. Biomarker of focal segmental glomerulosclerosis and schizophrenia. [provided by Alliance of Genome Resources, Apr 2022]

Target ID GM-T25464
Target Name PPP3CA
Gene Group ldentifer
（Target Gene ID in Homo species) 		5530
Gene ID 100067434 (Equus caballus), 101097144 (Felis catus), 19055 (Mus musculus), 24674 (Rattus norvegicus)
286852 (Bos taurus), 403486 (Canis lupus familiaris), 5530 (Homo sapiens), 709773 (Macaca mulatta)
Target Alternative Names 2900074D19Rik,ACCIID,CALN,CALNA,CALNA1,CAM-PRP catalytic subunit,CCN1,CN,CNA1,Calcineurin A alpha,Calmodulin-dependent calcineurin A subunit alpha isoform (CNA alpha),Caln,Calna,Calna1,CnA,DEE91,IECEE,IECEE1,PPP2B,PPP3CA,Ppp3ca,Protein phosphatase 3 catalytic subunit alpha,Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
Uniprot Accession P63328,P63329,P48452,Q08209
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease from KEGG MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Cellular senescence, Wnt signaling pathway, Axon guidance, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Renin secretion, Alzheimer disease, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis
Gene Ensembl ENSECAG00000010136, ENSMUSG00000028161, ENSBTAG00000016005, ENSCAFG00845024635, ENSG00000138814, ENSMMUG00000004599


Pre-made viral vector of PPP3CA cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP-SPh-124Human PPP3CA/CALN/CALNA Lentivirus plasmidNM_000944.45530HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAP-SPh-264Human PPP3CA/CALN/CALNA Adenovirus plasmidNM_000944.45530HumanAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMLP-SPh-124Human PPP3CA/CALN/CALNA Lentivirus particleNM_000944.45530HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAP-SPh-264Human PPP3CA/CALN/CALNA Adenovirus particleNM_000944.45530HumanAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
pGMAD001606Mouse Ppp3ca/2900074D19Rik/Caln Adenovirus plasmidNM_008913.519055MouseAdenovirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMLP-SPm-112Mouse Ppp3ca/2900074D19Rik/Caln Lentivirus plasmidNM_00891319055MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAP-SPm-239Mouse Ppp3ca/2900074D19Rik/Caln Adenovirus plasmidNM_00891319055MouseAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMAD001606Mouse Ppp3ca/2900074D19Rik/Caln Adenovirus particleNM_008913.519055MouseAdenovirus particleNull3xflag (C-Terminal)CMVDetail
vGMLP-SPm-112Mouse Ppp3ca/2900074D19Rik/Caln Lentivirus particleNM_00891319055MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAP-SPm-239Mouse Ppp3ca/2900074D19Rik/Caln Adenovirus particleNM_00891319055MouseAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail


PPP3CA siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo5530Pre-made Human PPP3CA/CALN/CCN1 siRNA oligo Duplex5530HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo24674Pre-made Rat Ppp3ca/Calna1 siRNA oligo Duplex24674RatIn-vitro grade; in-vivo gradeDetail
pGMoligo19055Pre-made Mouse Ppp3ca/CN/CnA siRNA oligo Duplex19055MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo709773Pre-made Cynomolgus/Rhesus macaque PPP3CA siRNA oligo Duplex709773Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101097144Pre-made Cat/Feline PPP3CA siRNA oligo Duplex101097144Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo403486Pre-made Dog/Canine PPP3CA siRNA oligo Duplex403486Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo286852Pre-made Bovines/Cattle PPP3CA siRNA oligo Duplex286852Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100067434Pre-made Equine/Horse PPP3CA siRNA oligo Duplex100067434Equine/HorseIn-vitro grade; in-vivo gradeDetail


PPP3CA antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T25464-AbHumanAnti-Human PPP3CA monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T25464-AbRatAnti-Rat PPP3CA monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T25464-AbMouseAnti-Mouse PPP3CA monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T25464-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque PPP3CA monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T25464-AbCat/FelineAnti-Cat/Feline PPP3CA monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T25464-AbDog/CanineAnti-Dog/Canine PPP3CA monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T25464-AbBovines/CattleAnti-Bovines/Cattle PPP3CA monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T25464-AbEquine/HorseAnti-Equine/Horse PPP3CA monoclonal antibodymabTherapeutics Target antibodyDetail


PPP3CA recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T25464-AgHumanHuman PPP3CA recombinant proteinMammalian cellDetail
GM-Tg-rg-T25464-AgRatRat PPP3CA recombinant proteinMammalian cellDetail
GM-Tg-mg-T25464-AgMouseMouse PPP3CA recombinant proteinMammalian cellDetail
GM-Tg-cynog-T25464-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque PPP3CA recombinant proteinMammalian cellDetail
GM-Tg-felg-T25464-AgCat/FelineCat/Feline PPP3CA recombinant proteinMammalian cellDetail
GM-Tg-cang-T25464-AgDog/CanineDog/Canine PPP3CA recombinant proteinMammalian cellDetail
GM-Tg-bovg-T25464-AgBovines/CattleBovines/Cattle PPP3CA recombinant proteinMammalian cellDetail
GM-Tg-equg-T25464-AgEquine/HorseEquine/Horse PPP3CA recombinant proteinMammalian cellDetail