Explore PPP3CA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
Enables several functions, including ATPase binding activity; calmodulin binding activity; and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; peptidyl-serine dephosphorylation; and response to calcium ion. Located in several cellular components, including cytosol; dendritic spine; and nucleoplasm. Part of calcineurin complex. Colocalizes with cytoplasmic side of plasma membrane. Implicated in developmental and epileptic encephalopathy 91. Biomarker of focal segmental glomerulosclerosis and schizophrenia. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T25464
|
| Target Name |
PPP3CA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5530
|
| Gene ID |
100067434 (Equus caballus), 101097144 (Felis catus), 19055 (Mus musculus), 24674 (Rattus norvegicus)
286852 (Bos taurus), 403486 (Canis lupus familiaris), 5530 (Homo sapiens), 709773 (Macaca mulatta)
|
| Target Alternative Names |
PPP3CA,Ppp3ca,CN,CnA,Caln,Calna,2900074D19Rik,Calna1,CALN,CCN1,CNA1,CALNA,DEE91,IECEE,PPP2B,ACCIID,CALNA1,IECEE1
|
| Uniprot Accession |
P63328,P63329,P48452,Q08209
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Cellular senescence, Wnt signaling pathway, Axon guidance, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Renin secretion, Alzheimer disease, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000010136, ENSMUSG00000028161, ENSBTAG00000016005, ENSCAFG00845024635, ENSG00000138814, ENSMMUG00000004599
|
| Target Classification |
|
Pre-made viral vector of PPP3CA cDNA Clones/ORF Plasmid
PPP3CA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5530 | Pre-made Human PPP3CA/CALN/CCN1 siRNA oligo Duplex | 5530 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24674 | Pre-made Rat Ppp3ca/Calna1 siRNA oligo Duplex | 24674 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19055 | Pre-made Mouse Ppp3ca/CN/CnA siRNA oligo Duplex | 19055 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709773 | Pre-made Cynomolgus/Rhesus macaque PPP3CA siRNA oligo Duplex | 709773 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097144 | Pre-made Cat/Feline PPP3CA siRNA oligo Duplex | 101097144 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403486 | Pre-made Dog/Canine PPP3CA siRNA oligo Duplex | 403486 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo286852 | Pre-made Bovines/Cattle PPP3CA siRNA oligo Duplex | 286852 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067434 | Pre-made Equine/Horse PPP3CA siRNA oligo Duplex | 100067434 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PPP3CA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T25464-Ab | Human | Anti-Human PPP3CA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T25464-Ab | Rat | Anti-Rat PPP3CA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T25464-Ab | Mouse | Anti-Mouse PPP3CA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T25464-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PPP3CA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T25464-Ab | Cat/Feline | Anti-Cat/Feline PPP3CA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T25464-Ab | Dog/Canine | Anti-Dog/Canine PPP3CA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T25464-Ab | Bovines/Cattle | Anti-Bovines/Cattle PPP3CA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T25464-Ab | Equine/Horse | Anti-Equine/Horse PPP3CA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PPP3CA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T25464-Ag | Human | Human PPP3CA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T25464-Ag | Rat | Rat PPP3CA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T25464-Ag | Mouse | Mouse PPP3CA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T25464-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PPP3CA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T25464-Ag | Cat/Feline | Cat/Feline PPP3CA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T25464-Ag | Dog/Canine | Dog/Canine PPP3CA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T25464-Ag | Bovines/Cattle | Bovines/Cattle PPP3CA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T25464-Ag | Equine/Horse | Equine/Horse PPP3CA recombinant protein | Mammalian cell | Detail |
