Recombinant multi-species PPP3CA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPP3CA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Enables several functions, including ATPase binding activity; calmodulin binding activity; and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; peptidyl-serine dephosphorylation; and response to calcium ion. Located in several cellular components, including cytosol; dendritic spine; and nucleoplasm. Part of calcineurin complex. Colocalizes with cytoplasmic side of plasma membrane. Implicated in developmental and epileptic encephalopathy 91. Biomarker of focal segmental glomerulosclerosis and schizophrenia. [provided by Alliance of Genome Resources, Apr 2022]
The Alternative Names of target: PPP3CA,Protein phosphatase 3 catalytic subunit alpha,CAM-PRP catalytic subunit, Calcineurin A alpha, Calmodulin-dependent calcineurin A subunit alpha isoform (CNA alpha), Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform,CALN,CCN1,CNA1,CALNA,DEE91,IECEE,PPP2B,ACCIID,CALNA1,IECEE1

Target products collectionGo to PPP3CA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T25464-Ag-1/ GM-Tg-hg-T25464-Ag-2 Human PPP3CA protein Human
GM-Tg-rg-T25464-Ag-1/ GM-Tg-rg-T25464-Ag-2 Rat PPP3CA protein Rat
GM-Tg-mg-T25464-Ag-1/ GM-Tg-mg-T25464-Ag-2 Mouse PPP3CA protein Mouse
GM-Tg-cynog-T25464-Ag-1/ GM-Tg-cynog-T25464-Ag-2 Cynomolgus/Rhesus macaque PPP3CA monoclonal antigen Cynomolgus/ Rhesus macaque
GM-Tg-felg-T25464-Ag-1/ GM-Tg-felg-T25464-Ag-2 Feline PPP3CA protein Feline
GM-Tg-cang-T25464-Ag-1/ GM-Tg-cang-T25464-Ag-2 Canine PPP3CA protein Canine
GM-Tg-bovg-T25464-Ag-1/ GM-Tg-bovg-T25464-Ag-2 Bovine PPP3CA protein Bovine
GM-Tg-equg-T25464-Ag-1/ GM-Tg-equg-T25464-Ag-2 Equine PPP3CA protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T25464-Ag-1/ GM-Tg-hg-T25464-Ag-2; GM-Tg-rg-T25464-Ag-1/ GM-Tg-rg-T25464-Ag-2;
GM-Tg-mg-T25464-Ag-1/ GM-Tg-mg-T25464-Ag-2; GM-Tg-cynog-T25464-Ag-1/ GM-Tg-cynog-T25464-Ag-2;
GM-Tg-felg-T25464-Ag-1/ GM-Tg-felg-T25464-Ag-2; GM-Tg-cang-T25464-Ag-1/ GM-Tg-cang-T25464-Ag-2;
GM-Tg-bovg-T25464-Ag-1/ GM-Tg-bovg-T25464-Ag-2; GM-Tg-equg-T25464-Ag-1/ GM-Tg-equg-T25464-Ag-2
Products Name PPP3CA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PPP3CA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPP3CA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.