Explore GH1/HGH gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T19784
|
| Target Name |
GH1/HGH
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2688
|
| Gene ID |
14599 (Mus musculus), 24391 (Rattus norvegicus), 2688 (Homo sapiens), 493931 (Felis catus) 718156 (Macaca mulatta)
|
| Target Alternative Names |
GH,GH-N,GH-N),GH1,GHB3,GHB5,GHN,Gh,Gh1,Ghb1,Growth hormone (GH,Growth hormone 1,HGH,IGHD1A,IGHD1B,IGHD2,Pituitary growth hormone,RNGHGP,Somatotropin,hGH-N
|
| Uniprot Accession |
P06880,P01244,P01241,P46404,P33093
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
Ovary Cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Growth hormone synthesis, secretion and action
|
| Gene Ensembl |
ENSMUSG00000020713, ENSG00000259384, ENSMMUG00000039847
|
Pre-made viral vector of GH1/HGH cDNA Clones/ORF Plasmid
GH1/HGH siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2688 | Pre-made Human GH1/GH/GHN siRNA oligo Duplex | 2688 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24391 | Pre-made Rat Gh1/Gh/Ghb1 siRNA oligo Duplex | 24391 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14599 | Pre-made Mouse Gh/Gh1/Ghb1 siRNA oligo Duplex | 14599 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718156 | Pre-made Cynomolgus/Rhesus macaque GH1/GHB3 siRNA oligo Duplex | 718156 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493931 | Pre-made Cat/Feline GH1/GH siRNA oligo Duplex | 493931 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
GH1/HGH antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T19784-Ab | Human | Anti-Human GH1/HGH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T19784-Ab | Rat | Anti-Rat GH1/HGH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T19784-Ab | Mouse | Anti-Mouse GH1/HGH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T19784-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GH1/HGH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T19784-Ab | Cat/Feline | Anti-Cat/Feline GH1/HGH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GH1/HGH recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T19784-Ag | Human | Human GH1/HGH recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T19784-Ag | Rat | Rat GH1/HGH recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T19784-Ag | Mouse | Mouse GH1/HGH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T19784-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GH1/HGH recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T19784-Ag | Cat/Feline | Cat/Feline GH1/HGH recombinant protein | Mammalian cell | Detail |