Recombinant multi-species GH1/HGH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GH1/HGH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008]
The Alternative Names of target: GH,GH-N,GH-N),GH1,GHB3,GHB5,GHN,Gh,Gh1,Ghb1,Growth hormone (GH,Growth hormone 1,HGH,IGHD1A,IGHD1B,IGHD2,Pituitary growth hormone,RNGHGP,Somatotropin,hGH-N

Target products collectionGo to GH1/HGH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T19784-Ag-1/ GM-Tg-hg-T19784-Ag-2 Human GH1/HGH protein Human
GM-Tg-rg-T19784-Ag-1/ GM-Tg-rg-T19784-Ag-2 Rat GH1/HGH protein Rat
GM-Tg-mg-T19784-Ag-1/ GM-Tg-mg-T19784-Ag-2 Mouse GH1/HGH protein Mouse
GM-Tg-cynog-T19784-Ag-1/ GM-Tg-cynog-T19784-Ag-2 Cynomolgus/Rhesus macaque GH1/HGH protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T19784-Ag-1/ GM-Tg-felg-T19784-Ag-2 Feline GH1/HGH protein Feline
GM-Tg-cang-T19784-Ag-1/ GM-Tg-cang-T19784-Ag-2 Canine GH1/HGH protein Canine
GM-Tg-bovg-T19784-Ag-1/ GM-Tg-bovg-T19784-Ag-2 Bovine GH1/HGH protein Bovine
GM-Tg-equg-T19784-Ag-1/ GM-Tg-equg-T19784-Ag-2 Equine GH1/HGH protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T19784-Ag-1/ GM-Tg-hg-T19784-Ag-2; GM-Tg-rg-T19784-Ag-1/ GM-Tg-rg-T19784-Ag-2;
GM-Tg-mg-T19784-Ag-1/ GM-Tg-mg-T19784-Ag-2; GM-Tg-cynog-T19784-Ag-1/ GM-Tg-cynog-T19784-Ag-2;
GM-Tg-felg-T19784-Ag-1/ GM-Tg-felg-T19784-Ag-2; GM-Tg-cang-T19784-Ag-1/ GM-Tg-cang-T19784-Ag-2;
GM-Tg-bovg-T19784-Ag-1/ GM-Tg-bovg-T19784-Ag-2; GM-Tg-equg-T19784-Ag-1/ GM-Tg-equg-T19784-Ag-2
Products Name GH1/HGH protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GH1/HGH
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GH1/HGH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.