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Target
sublocation: Introcelluar Protein.
This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Target ID |
GM-T17221
|
Target Name |
GSTA1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2938
|
Gene ID |
2938 (Homo sapiens)
|
Target Alternative Names |
GSTA1,GST2,GTH1,GSTA1-1,GST-epsilon
|
Uniprot Accession |
P08263
|
Uniprot Entry Name |
|
Protein Sub-location |
Introcelluar Protein
|
Category |
Therapeutics Target
|
Disease |
cancer, Prostate Cancer
|
Disease from KEGG |
Metabolic pathways, Pathways in cancer, Chemical carcinogenesis - DNA adducts, Chemical carcinogenesis - receptor activation, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis, Drug metabolism - cytochrome P450
|
Gene Ensembl |
ENSG00000243955
|
Target Classification |
|
Pre-made viral vector of GSTA1 cDNA Clones/ORF Plasmid
GSTA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo2938 | Pre-made Human GSTA1/GST2/GTH1 siRNA oligo Duplex | 2938 | Human | In-vitro grade; in-vivo grade | Detail |
GSTA1 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T17221-Ab | Human | Anti-Human GSTA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GSTA1 recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T17221-Ag | Human | Human GSTA1 recombinant protein | Mammalian cell | Detail |