Recombinant multi-species GSTA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GSTA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
The Alternative Names of target: GSTA1,Glutathione S-transferase A1,13-hydroperoxyoctadecadienoate peroxidase, Androst-5-ene-3,17-dione isomerase, GST HA subunit 1, GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1,GST2,GTH1,GSTA1-1,GST-epsilon
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T17221-Ab-1/ GM-Tg-hg-T17221-Ab-2 | Human GSTA1 protein | Human |
GM-Tg-rg-T17221-Ab-1/ GM-Tg-rg-T17221-Ab-2 | Rat GSTA1 protein | Rat |
GM-Tg-mg-T17221-Ab-1/ GM-Tg-mg-T17221-Ab-2 | Mouse GSTA1 protein | Mouse |
GM-Tg-cynog-T17221-Ab-1/ GM-Tg-cynog-T17221-Ab-2 | Cynomolgus/Rhesus macaque GSTA1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T17221-Ab-1/ GM-Tg-felg-T17221-Ab-2 | Feline GSTA1 protein | Feline |
GM-Tg-cang-T17221-Ab-1/ GM-Tg-cang-T17221-Ab-2 | Canine GSTA1 protein | Canine |
GM-Tg-bovg-T17221-Ab-1/ GM-Tg-bovg-T17221-Ab-2 | Bovine GSTA1 protein | Bovine |
GM-Tg-equg-T17221-Ab-1/ GM-Tg-equg-T17221-Ab-2 | Equine GSTA1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T17221-Ab-1/ GM-Tg-hg-T17221-Ab-2;
GM-Tg-rg-T17221-Ab-1/ GM-Tg-rg-T17221-Ab-2;
GM-Tg-mg-T17221-Ab-1/ GM-Tg-mg-T17221-Ab-2; GM-Tg-cynog-T17221-Ab-1/ GM-Tg-cynog-T17221-Ab-2; GM-Tg-felg-T17221-Ab-1/ GM-Tg-felg-T17221-Ab-2; GM-Tg-cang-T17221-Ab-1/ GM-Tg-cang-T17221-Ab-2; GM-Tg-bovg-T17221-Ab-1/ GM-Tg-bovg-T17221-Ab-2; GM-Tg-equg-T17221-Ab-1/ GM-Tg-equg-T17221-Ab-2 |
Products Name | GSTA1 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | GSTA1 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GSTA1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.