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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1. [provided by RefSeq, Oct 2015]
Target ID |
GM-SE0373
|
Target Name |
NPPA
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4878
|
Gene ID |
100034201 (Equus caballus), 101100575 (Felis catus), 230899 (Mus musculus), 24602 (Rattus norvegicus) 281355 (Bos taurus), 4878 (Homo sapiens), 608289 (Canis lupus familiaris), 714994 (Macaca mulatta)
|
Target Alternative Names |
NPPA,Nppa,CDD,proANF,proANP,preproANF,preproANP,ANP,Anf,Pnd,ANF,RATANF,CDP,PND,ATFB6,ATRST2,CDD-ANF
|
Uniprot Accession |
P27104,Q9GLD0,P05125,P01161,P07501,P01160,P07499
|
Uniprot Entry Name |
|
Protein Sub-location |
Secreted Protein/Potential Cytokines
|
Category |
Diagnostics Biomarker
|
Disease |
|
Disease from KEGG |
cGMP-PKG signaling pathway, cAMP signaling pathway, HIF-1 signaling pathway, Vascular smooth muscle contraction, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Aldosterone synthesis and secretion, African trypanosomiasis
|
Gene Ensembl |
ENSECAG00000014892, ENSMUSG00000041616, ENSBTAG00000006709, ENSG00000175206, ENSCAFG00845001994, ENSMMUG00000007834
|
Target Classification |
|
Pre-made viral vector of NPPA cDNA Clones/ORF Plasmid
NPPA siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo4878 | Pre-made Human NPPA/ANF/ANP siRNA oligo Duplex | 4878 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo24602 | Pre-made Rat Nppa/ANF/ANP siRNA oligo Duplex | 24602 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo230899 | Pre-made Mouse Nppa/ANP/Anf siRNA oligo Duplex | 230899 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo714994 | Pre-made Cynomolgus/Rhesus macaque NPPA siRNA oligo Duplex | 714994 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101100575 | Pre-made Cat/Feline NPPA/CDD/proANF siRNA oligo Duplex | 101100575 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo608289 | Pre-made Dog/Canine NPPA/ANF/ANP siRNA oligo Duplex | 608289 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo281355 | Pre-made Bovines/Cattle NPPA/CDD siRNA oligo Duplex | 281355 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100034201 | Pre-made Equine/Horse NPPA/CDD siRNA oligo Duplex | 100034201 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NPPA antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-SE0373-Ab | Human | Anti-Human NPPA monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
GM-Tg-rg-SE0373-Ab | Rat | Anti-Rat NPPA monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
GM-Tg-mg-SE0373-Ab | Mouse | Anti-Mouse NPPA monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
GM-Tg-cynog-SE0373-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NPPA monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
GM-Tg-felg-SE0373-Ab | Cat/Feline | Anti-Cat/Feline NPPA monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
GM-Tg-cang-SE0373-Ab | Dog/Canine | Anti-Dog/Canine NPPA monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
GM-Tg-bovg-SE0373-Ab | Bovines/Cattle | Anti-Bovines/Cattle NPPA monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
GM-Tg-equg-SE0373-Ab | Equine/Horse | Anti-Equine/Horse NPPA monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
NPPA recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-SE0373-Ag | Human | Human NPPA recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-SE0373-Ag | Rat | Rat NPPA recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-SE0373-Ag | Mouse | Mouse NPPA recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-SE0373-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NPPA recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-SE0373-Ag | Cat/Feline | Cat/Feline NPPA recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-SE0373-Ag | Dog/Canine | Dog/Canine NPPA recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-SE0373-Ag | Bovines/Cattle | Bovines/Cattle NPPA recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-SE0373-Ag | Equine/Horse | Equine/Horse NPPA recombinant protein | Mammalian cell | Detail |