Recombinant multi-species NPPA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NPPA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1. [provided by RefSeq, Oct 2015]
The Alternative Names of target: NPPA,Natriuretic peptides A,Atrial natriuretic factor prohormone (proANF), Atrial natriuretic peptide prohormone (preproANP, proANP), Atriopeptigen, Cardiodilatin (CDD), preproCDD-ANF,ANF,ANP,CDD,CDP,PND,ATFB6,ATRST2,CDD-ANF

Target products collectionGo to NPPA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0373-Ab-1/ GM-Tg-hg-SE0373-Ab-2 Human NPPA protein Human
GM-Tg-rg-SE0373-Ab-1/ GM-Tg-rg-SE0373-Ab-2 Rat NPPA protein Rat
GM-Tg-mg-SE0373-Ab-1/ GM-Tg-mg-SE0373-Ab-2 Mouse NPPA protein Mouse
GM-Tg-cynog-SE0373-Ab-1/ GM-Tg-cynog-SE0373-Ab-2 Cynomolgus/Rhesus macaque NPPA monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0373-Ab-1/ GM-Tg-felg-SE0373-Ab-2 Feline NPPA protein Feline
GM-Tg-cang-SE0373-Ab-1/ GM-Tg-cang-SE0373-Ab-2 Canine NPPA protein Canine
GM-Tg-bovg-SE0373-Ab-1/ GM-Tg-bovg-SE0373-Ab-2 Bovine NPPA protein Bovine
GM-Tg-equg-SE0373-Ab-1/ GM-Tg-equg-SE0373-Ab-2 Equine NPPA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0373-Ab-1/ GM-Tg-hg-SE0373-Ab-2; GM-Tg-rg-SE0373-Ab-1/ GM-Tg-rg-SE0373-Ab-2;
GM-Tg-mg-SE0373-Ab-1/ GM-Tg-mg-SE0373-Ab-2; GM-Tg-cynog-SE0373-Ab-1/ GM-Tg-cynog-SE0373-Ab-2;
GM-Tg-felg-SE0373-Ab-1/ GM-Tg-felg-SE0373-Ab-2; GM-Tg-cang-SE0373-Ab-1/ GM-Tg-cang-SE0373-Ab-2;
GM-Tg-bovg-SE0373-Ab-1/ GM-Tg-bovg-SE0373-Ab-2; GM-Tg-equg-SE0373-Ab-1/ GM-Tg-equg-SE0373-Ab-2
Products Name NPPA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NPPA
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NPPA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.