Explore FGF19 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0215
|
| Target Name |
FGF19
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9965
|
| Gene ID |
100060488 (Equus caballus), 101087099 (Felis catus), 14170 (Mus musculus), 170582 (Rattus norvegicus)
483681 (Canis lupus familiaris), 521475 (Bos taurus), 709109 (Macaca mulatta), 9965 (Homo sapiens)
|
| Target Alternative Names |
FGF-19,FGF19,FGF8A,Fgf15,Fgf19,Fgf8a,Fibroblast growth factor 19
|
| Uniprot Accession |
O35622,O95750
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Melanoma, Breast cancer, Gastric cancer
|
| Gene Ensembl |
ENSECAG00000036646, ENSMUSG00000031073, ENSCAFG00845015136, ENSBTAG00000017285, ENSMMUG00000053386, ENSG00000162344
|
Pre-made viral vector of FGF19 cDNA Clones/ORF Plasmid
FGF19 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9965 | Pre-made Human FGF19 siRNA oligo Duplex | 9965 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo170582 | Pre-made Rat Fgf19/Fgf15/Fgf8a siRNA oligo Duplex | 170582 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14170 | Pre-made Mouse Fgf15/FGF19/Fgf8a siRNA oligo Duplex | 14170 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709109 | Pre-made Cynomolgus/Rhesus macaque FGF19 siRNA oligo Duplex | 709109 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087099 | Pre-made Cat/Feline FGF19 siRNA oligo Duplex | 101087099 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483681 | Pre-made Dog/Canine FGF19 siRNA oligo Duplex | 483681 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo521475 | Pre-made Bovines/Cattle FGF19/FGF8A siRNA oligo Duplex | 521475 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060488 | Pre-made Equine/Horse FGF19 siRNA oligo Duplex | 100060488 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FGF19 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0215-Ab | Human | Anti-Human FGF19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0215-Ab | Rat | Anti-Rat FGF19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0215-Ab | Mouse | Anti-Mouse FGF19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0215-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FGF19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0215-Ab | Cat/Feline | Anti-Cat/Feline FGF19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0215-Ab | Dog/Canine | Anti-Dog/Canine FGF19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0215-Ab | Bovines/Cattle | Anti-Bovines/Cattle FGF19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0215-Ab | Equine/Horse | Anti-Equine/Horse FGF19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
FGF19 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0215-Ag | Human | Human FGF19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0215-Ag | Rat | Rat FGF19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0215-Ag | Mouse | Mouse FGF19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0215-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FGF19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0215-Ag | Cat/Feline | Cat/Feline FGF19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0215-Ag | Dog/Canine | Dog/Canine FGF19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0215-Ag | Bovines/Cattle | Bovines/Cattle FGF19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0215-Ag | Equine/Horse | Equine/Horse FGF19 recombinant protein | Mammalian cell | Detail |
