Explore FKBP1A gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008]
Target ID |
GM-IP0019
|
Target Name |
FKBP1A
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2280
|
Gene ID |
100629541 (Equus caballus), 100686033 (Canis lupus familiaris), 101100379 (Felis catus), 14225 (Mus musculus) 2280 (Homo sapiens), 25639 (Rattus norvegicus), 614795 (Bos taurus), 717385 (Macaca mulatta)
|
Target Alternative Names |
FKBP1A,Fkbp1a,Fkbp,Fkbp1,FKBP12,FKBP1,PKC12,PKCI2,PPIASE,FKBP-12,FKBP-1A,Fkbp2,FKBP1B
|
Uniprot Accession |
P26883,P62942,Q62658,P18203
|
Uniprot Entry Name |
|
Protein Sub-location |
Introcelluar Protein
|
Category |
Therapeutics Target
|
Disease |
|
Disease from KEGG |
|
Gene Ensembl |
ENSECAG00000017887, ENSCAFG00845018977, ENSMUSG00000032966, ENSG00000088832, ENSBTAG00000008303, ENSMMUG00000015996
|
Target Classification |
|
Pre-made viral vector of FKBP1A cDNA Clones/ORF Plasmid
FKBP1A siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo2280 | Pre-made Human FKBP1A/FKBP1/PKC12 siRNA oligo Duplex | 2280 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo25639 | Pre-made Rat Fkbp1a/Fkbp2/FKBP12 siRNA oligo Duplex | 25639 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo14225 | Pre-made Mouse Fkbp1a/Fkbp/Fkbp1 siRNA oligo Duplex | 14225 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo717385 | Pre-made Cynomolgus/Rhesus macaque FKBP1A siRNA oligo Duplex | 717385 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101100379 | Pre-made Cat/Feline FKBP1A siRNA oligo Duplex | 101100379 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo100686033 | Pre-made Dog/Canine FKBP1A siRNA oligo Duplex | 100686033 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo614795 | Pre-made Bovines/Cattle FKBP1A/FKBP1B siRNA oligo Duplex | 614795 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100629541 | Pre-made Equine/Horse FKBP1A siRNA oligo Duplex | 100629541 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FKBP1A antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-IP0019-Ab | Human | Anti-Human FKBP1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-rg-IP0019-Ab | Rat | Anti-Rat FKBP1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-mg-IP0019-Ab | Mouse | Anti-Mouse FKBP1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cynog-IP0019-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FKBP1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-felg-IP0019-Ab | Cat/Feline | Anti-Cat/Feline FKBP1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cang-IP0019-Ab | Dog/Canine | Anti-Dog/Canine FKBP1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-bovg-IP0019-Ab | Bovines/Cattle | Anti-Bovines/Cattle FKBP1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-equg-IP0019-Ab | Equine/Horse | Anti-Equine/Horse FKBP1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
FKBP1A recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-IP0019-Ag | Human | Human FKBP1A recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-IP0019-Ag | Rat | Rat FKBP1A recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-IP0019-Ag | Mouse | Mouse FKBP1A recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-IP0019-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FKBP1A recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-IP0019-Ag | Cat/Feline | Cat/Feline FKBP1A recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-IP0019-Ag | Dog/Canine | Dog/Canine FKBP1A recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-IP0019-Ag | Bovines/Cattle | Bovines/Cattle FKBP1A recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-IP0019-Ag | Equine/Horse | Equine/Horse FKBP1A recombinant protein | Mammalian cell | Detail |