Explore SIGMAR1/OPRS1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2013]
| Target ID |
GM-IP0013
|
| Target Name |
SIGMAR1/OPRS1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
10280
|
| Gene ID |
100068507 (Equus caballus), 101084912 (Felis catus), 10280 (Homo sapiens), 18391 (Mus musculus) 29336 (Rattus norvegicus), 481587 (Canis lupus familiaris), 538903 (Bos taurus), 700469 (Macaca mulatta)
|
| Target Alternative Names |
ALS16,Aging-associated gene 8 protein,DSMA2,HMNR2,OPRS1,Oprs1,SIG-1R,SIGMAR1,SR-BP,SR-BP1,SR31747-binding protein (SR-BP),SRBP,Sig1R,Sigma 1-type opioid receptor (SIG-1R,Sigma non-opioid intracellular receptor 1,Sigma1-receptor,Sigma1R,Sigmar1,hSigmaR1,hSigmaR1),sigma1R
|
| Uniprot Accession |
Q99720,O55242,Q9R0C9,Q58DH7
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000019783, ENSG00000147955, ENSMUSG00000036078, ENSCAFG00845024716, ENSBTAG00000015804, ENSMMUG00000020774
|
Pre-made viral vector of SIGMAR1/OPRS1 cDNA Clones/ORF Plasmid
SIGMAR1/OPRS1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10280 | Pre-made Human SIGMAR1/SRBP/ALS16 siRNA oligo Duplex | 10280 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29336 | Pre-made Rat Sigmar1/Oprs1 siRNA oligo Duplex | 29336 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18391 | Pre-made Mouse Sigmar1/Oprs1/Sig1R siRNA oligo Duplex | 18391 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700469 | Pre-made Cynomolgus/Rhesus macaque SIGMAR1 siRNA oligo Duplex | 700469 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084912 | Pre-made Cat/Feline SIGMAR1 siRNA oligo Duplex | 101084912 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481587 | Pre-made Dog/Canine SIGMAR1/OPRS1 siRNA oligo Duplex | 481587 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo538903 | Pre-made Bovines/Cattle SIGMAR1/OPRS1 siRNA oligo Duplex | 538903 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068507 | Pre-made Equine/Horse SIGMAR1 siRNA oligo Duplex | 100068507 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SIGMAR1/OPRS1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0013-Ab | Human | Anti-Human SIGMAR1/OPRS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0013-Ab | Rat | Anti-Rat SIGMAR1/OPRS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0013-Ab | Mouse | Anti-Mouse SIGMAR1/OPRS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0013-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SIGMAR1/OPRS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0013-Ab | Cat/Feline | Anti-Cat/Feline SIGMAR1/OPRS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0013-Ab | Dog/Canine | Anti-Dog/Canine SIGMAR1/OPRS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0013-Ab | Bovines/Cattle | Anti-Bovines/Cattle SIGMAR1/OPRS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0013-Ab | Equine/Horse | Anti-Equine/Horse SIGMAR1/OPRS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
SIGMAR1/OPRS1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0013-Ag | Human | Human SIGMAR1/OPRS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0013-Ag | Rat | Rat SIGMAR1/OPRS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0013-Ag | Mouse | Mouse SIGMAR1/OPRS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0013-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SIGMAR1/OPRS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0013-Ag | Cat/Feline | Cat/Feline SIGMAR1/OPRS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0013-Ag | Dog/Canine | Dog/Canine SIGMAR1/OPRS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0013-Ag | Bovines/Cattle | Bovines/Cattle SIGMAR1/OPRS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0013-Ag | Equine/Horse | Equine/Horse SIGMAR1/OPRS1 recombinant protein | Mammalian cell | Detail |