Recombinant multi-species SIGMAR1/OPRS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SIGMAR1/OPRS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2013]
The Alternative Names of target: ALS16,Aging-associated gene 8 protein,DSMA2,HMNR2,OPRS1,Oprs1,SIG-1R,SIGMAR1,SR-BP,SR-BP1,SR31747-binding protein (SR-BP),SRBP,Sig1R,Sigma 1-type opioid receptor (SIG-1R,Sigma non-opioid intracellular receptor 1,Sigma1-receptor,Sigma1R,Sigmar1,hSigmaR1,hSigmaR1),sigma1R
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0013-Ag-1/ GM-Tg-hg-IP0013-Ag-2 | Human SIGMAR1/OPRS1 protein | Human |
| GM-Tg-rg-IP0013-Ag-1/ GM-Tg-rg-IP0013-Ag-2 | Rat SIGMAR1/OPRS1 protein | Rat |
| GM-Tg-mg-IP0013-Ag-1/ GM-Tg-mg-IP0013-Ag-2 | Mouse SIGMAR1/OPRS1 protein | Mouse |
| GM-Tg-cynog-IP0013-Ag-1/ GM-Tg-cynog-IP0013-Ag-2 | Cynomolgus/Rhesus macaque SIGMAR1/OPRS1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0013-Ag-1/ GM-Tg-felg-IP0013-Ag-2 | Feline SIGMAR1/OPRS1 protein | Feline |
| GM-Tg-cang-IP0013-Ag-1/ GM-Tg-cang-IP0013-Ag-2 | Canine SIGMAR1/OPRS1 protein | Canine |
| GM-Tg-bovg-IP0013-Ag-1/ GM-Tg-bovg-IP0013-Ag-2 | Bovine SIGMAR1/OPRS1 protein | Bovine |
| GM-Tg-equg-IP0013-Ag-1/ GM-Tg-equg-IP0013-Ag-2 | Equine SIGMAR1/OPRS1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP0013-Ag-1/ GM-Tg-hg-IP0013-Ag-2;
GM-Tg-rg-IP0013-Ag-1/ GM-Tg-rg-IP0013-Ag-2;
GM-Tg-mg-IP0013-Ag-1/ GM-Tg-mg-IP0013-Ag-2; GM-Tg-cynog-IP0013-Ag-1/ GM-Tg-cynog-IP0013-Ag-2; GM-Tg-felg-IP0013-Ag-1/ GM-Tg-felg-IP0013-Ag-2; GM-Tg-cang-IP0013-Ag-1/ GM-Tg-cang-IP0013-Ag-2; GM-Tg-bovg-IP0013-Ag-1/ GM-Tg-bovg-IP0013-Ag-2; GM-Tg-equg-IP0013-Ag-1/ GM-Tg-equg-IP0013-Ag-2 |
| Products Name | SIGMAR1/OPRS1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | SIGMAR1/OPRS1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SIGMAR1/OPRS1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
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exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
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reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.