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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008]
| Target ID |
GM-TA101
|
| Target Name |
VAMP2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6844
|
| Gene ID |
100073047 (Equus caballus), 101101516 (Felis catus), 22318 (Mus musculus), 24803 (Rattus norvegicus) 282116 (Bos taurus), 479491 (Canis lupus familiaris), 574134 (Macaca mulatta), 6844 (Homo sapiens)
|
| Target Alternative Names |
NEDHAHM,RATVAMPB,RATVAMPIR,SYB,SYB2,Syb-2,Syb2,Synaptobrevin-2,VAMP-2,VAMP2,Vamp-2,Vamp2,Vesicle-associated membrane protein 2,sybII
|
| Uniprot Accession |
P63044,P63045,P63026,Q9N0Y0,P63027
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
SNARE interactions in vesicular transport, Insulin secretion, Salivary secretion
|
| Gene Ensembl |
ENSECAG00000014189, ENSMUSG00000020894, ENSBTAG00000054934, ENSCAFG00845028001, ENSMMUG00000021798, ENSG00000220205
|
Pre-made viral vector of VAMP2 cDNA Clones/ORF Plasmid
VAMP2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6844 | Pre-made Human VAMP2/SYB2/VAMP-2 siRNA oligo Duplex | 6844 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24803 | Pre-made Rat Vamp2/SYB/Syb2 siRNA oligo Duplex | 24803 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22318 | Pre-made Mouse Vamp2/Syb2/Syb-2 siRNA oligo Duplex | 22318 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574134 | Pre-made Cynomolgus/Rhesus macaque VAMP2/SYB2/VAMP-2 siRNA oligo Duplex | 574134 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101516 | Pre-made Cat/Feline VAMP2 siRNA oligo Duplex | 101101516 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479491 | Pre-made Dog/Canine VAMP2 siRNA oligo Duplex | 479491 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282116 | Pre-made Bovines/Cattle VAMP2 siRNA oligo Duplex | 282116 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100073047 | Pre-made Equine/Horse VAMP2 siRNA oligo Duplex | 100073047 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
VAMP2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA101-Ab | Human | Anti-Human VAMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA101-Ab | Rat | Anti-Rat VAMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA101-Ab | Mouse | Anti-Mouse VAMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA101-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque VAMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA101-Ab | Cat/Feline | Anti-Cat/Feline VAMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA101-Ab | Dog/Canine | Anti-Dog/Canine VAMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA101-Ab | Bovines/Cattle | Anti-Bovines/Cattle VAMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA101-Ab | Equine/Horse | Anti-Equine/Horse VAMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
VAMP2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA101-Ag | Human | Human VAMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-TA101-Ag | Rat | Rat VAMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-TA101-Ag | Mouse | Mouse VAMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-TA101-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque VAMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-TA101-Ag | Cat/Feline | Cat/Feline VAMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-TA101-Ag | Dog/Canine | Dog/Canine VAMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-TA101-Ag | Bovines/Cattle | Bovines/Cattle VAMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-TA101-Ag | Equine/Horse | Equine/Horse VAMP2 VLP (virus-like particle) | HEK293 | Products Developing |