Explore VISTA/VSIR gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Enables endopeptidase activator activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of macromolecule metabolic process; and regulation of T cell activation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T99704
|
| Target Name |
VISTA/VSIR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
64115
|
| Gene ID |
101096355 (Felis catus), 102149832 (Equus caballus), 106558705 (Canis lupus familiaris), 64115 (Homo sapiens)
690899 (Rattus norvegicus), 709595 (Macaca mulatta), 74048 (Mus musculus), 783068 (Bos taurus)
|
| Target Alternative Names |
VSIR,Vsir,CD2H10orf54,C1H10orf54,C4H10orf54,B7H5,GI24,B7-H5,Dies1,PD-1H,SISP1,VISTA,PP2135,C10orf54,DD1alpha,C9orf54,C9H10orf54,4632428N05Rik,C28H10orf54
|
| Uniprot Accession |
Q9H7M9,Q9D659
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
|
| Disease from KEGG |
Cell adhesion molecules
|
| Gene Ensembl |
ENSECAG00000018133, ENSCAFG00845004580, ENSG00000107738, ENSMMUG00000012967, ENSMUSG00000020101, ENSBTAG00000010888
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of VISTA/VSIR cDNA Clones/ORF Plasmid
VISTA/VSIR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo64115 | Pre-made Human VSIR/B7H5/GI24 siRNA oligo Duplex | 64115 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo690899 | Pre-made Rat Vsir siRNA oligo Duplex | 690899 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo74048 | Pre-made Mouse Vsir/Dies1/PD-1H siRNA oligo Duplex | 74048 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709595 | Pre-made Cynomolgus/Rhesus macaque VSIR/C9orf54/C9H10orf54 siRNA oligo Duplex | 709595 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096355 | Pre-made Cat/Feline VSIR/CD2H10orf54 siRNA oligo Duplex | 101096355 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106558705 | Pre-made Dog/Canine VSIR/C4H10orf54 siRNA oligo Duplex | 106558705 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo783068 | Pre-made Bovines/Cattle VSIR/C28H10orf54 siRNA oligo Duplex | 783068 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102149832 | Pre-made Equine/Horse VSIR/C1H10orf54 siRNA oligo Duplex | 102149832 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
VISTA/VSIR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T99704-Ab | Human | Anti-Human VISTA/VSIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T99704-Ab | Rat | Anti-Rat VISTA/VSIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T99704-Ab | Mouse | Anti-Mouse VISTA/VSIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T99704-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque VISTA/VSIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T99704-Ab | Cat/Feline | Anti-Cat/Feline VISTA/VSIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T99704-Ab | Dog/Canine | Anti-Dog/Canine VISTA/VSIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T99704-Ab | Bovines/Cattle | Anti-Bovines/Cattle VISTA/VSIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T99704-Ab | Equine/Horse | Anti-Equine/Horse VISTA/VSIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
VISTA/VSIR VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T99704-Ag | Human | Human VISTA/VSIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T99704-Ag | Rat | Rat VISTA/VSIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T99704-Ag | Mouse | Mouse VISTA/VSIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T99704-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque VISTA/VSIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T99704-Ag | Cat/Feline | Cat/Feline VISTA/VSIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T99704-Ag | Dog/Canine | Dog/Canine VISTA/VSIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T99704-Ag | Bovines/Cattle | Bovines/Cattle VISTA/VSIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T99704-Ag | Equine/Horse | Equine/Horse VISTA/VSIR VLP (virus-like particle) | HEK293 | Products Developing |
