SMAD7 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore SMAD7 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

Target ID GM-T94695
Target Name SMAD7
Gene Group ldentifer
（Target Gene ID in Homo species) 		4092
Gene ID 100033853 (Equus caballus), 101088277 (Felis catus), 17131 (Mus musculus), 4092 (Homo sapiens)
490570 (Canis lupus familiaris), 535916 (Bos taurus), 698338 (Macaca mulatta), 81516 (Rattus norvegicus)
Target Alternative Names CRCS3,MAD homolog 7,MADH7,MADH8,Madh7,Mothers against DPP homolog 7,Mothers against DPP homolog 8),Mothers against decapentaplegic homolog 7,Mothers against decapentaplegic homolog 8 (MAD homolog 8,SMAD family member 7 (SMAD 7,SMAD7,Smad7,hSMAD7)
Uniprot Accession O35253,O15105,O88406
Uniprot Entry Name
Protein Sub-location Introcelluar Protein
Category Therapeutics Target, Cytokine Target
Disease cancer
Disease from KEGG TGF-beta signaling pathway, Hippo signaling pathway
Gene Ensembl ENSECAG00000020583, ENSMUSG00000025880, ENSG00000101665, ENSCAFG00845017036, ENSBTAG00000012441, ENSMMUG00000056276
Target Classification Tumor-associated antigen (TAA)


Pre-made viral vector of SMAD7 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP001429Human SMAD7/CRCS3/MADH7 Lentivirus plasmidNM_0059044092HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLP-SPh-049Human SMAD7/CRCS3/MADH7 Lentivirus plasmidNM_0059044092HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAP-SPh-189Human SMAD7/CRCS3/MADH7 Adenovirus plasmidNM_0059044092HumanAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMPC000433Human SMAD7/CRCS3/MADH7 Mammalian (Non-Viral Vector) plasmidNM_005904.44092HumanMammalian (Non-Viral Vector) plasmidNull3xflag (C-Terminal)CMVDetail
vGMLP001429Human SMAD7/CRCS3/MADH7 Lentivirus particleNM_0059044092HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLP-SPh-049Human SMAD7/CRCS3/MADH7 Lentivirus particleNM_0059044092HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAP-SPh-189Human SMAD7/CRCS3/MADH7 Adenovirus particleNM_0059044092HumanAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail


SMAD7 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo4092Pre-made Human SMAD7/CRCS3/MADH7 siRNA oligo Duplex4092HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo81516Pre-made Rat Smad7/Madh7 siRNA oligo Duplex81516RatIn-vitro grade; in-vivo gradeDetail
pGMoligo17131Pre-made Mouse Smad7/Madh7 siRNA oligo Duplex17131MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo698338Pre-made Cynomolgus/Rhesus macaque SMAD7 siRNA oligo Duplex698338Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101088277Pre-made Cat/Feline SMAD7 siRNA oligo Duplex101088277Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo490570Pre-made Dog/Canine SMAD7 siRNA oligo Duplex490570Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo535916Pre-made Bovines/Cattle SMAD7 siRNA oligo Duplex535916Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100033853Pre-made Equine/Horse SMAD7 siRNA oligo Duplex100033853Equine/HorseIn-vitro grade; in-vivo gradeDetail


SMAD7 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T94695-AbHumanAnti-Human SMAD7 monoclonal antibodymabTherapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-rg-T94695-AbRatAnti-Rat SMAD7 monoclonal antibodymabTherapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-mg-T94695-AbMouseAnti-Mouse SMAD7 monoclonal antibodymabTherapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-cynog-T94695-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque SMAD7 monoclonal antibodymabTherapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-felg-T94695-AbCat/FelineAnti-Cat/Feline SMAD7 monoclonal antibodymabTherapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-cang-T94695-AbDog/CanineAnti-Dog/Canine SMAD7 monoclonal antibodymabTherapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-bovg-T94695-AbBovines/CattleAnti-Bovines/Cattle SMAD7 monoclonal antibodymabTherapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-equg-T94695-AbEquine/HorseAnti-Equine/Horse SMAD7 monoclonal antibodymabTherapeutics Target antibody, Cytokine antibodyDetail


SMAD7 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T94695-AgHumanHuman SMAD7 recombinant proteinMammalian cellDetail
GM-Tg-rg-T94695-AgRatRat SMAD7 recombinant proteinMammalian cellDetail
GM-Tg-mg-T94695-AgMouseMouse SMAD7 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T94695-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque SMAD7 recombinant proteinMammalian cellDetail
GM-Tg-felg-T94695-AgCat/FelineCat/Feline SMAD7 recombinant proteinMammalian cellDetail
GM-Tg-cang-T94695-AgDog/CanineDog/Canine SMAD7 recombinant proteinMammalian cellDetail
GM-Tg-bovg-T94695-AgBovines/CattleBovines/Cattle SMAD7 recombinant proteinMammalian cellDetail
GM-Tg-equg-T94695-AgEquine/HorseEquine/Horse SMAD7 recombinant proteinMammalian cellDetail