Human SMAD7/CRCS3/MADH7 ORF/cDNA clone-Adenovirus particle (NM_005904)

Cat. No.: vGMAP-SPh-189

Pre-made Human SMAD7/CRCS3/MADH7 Adenovirus for SMAD7 overexpression in-vitro and in-vivo. The SMAD7 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified SMAD7-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.

Target products collection

Go to SMAD7/CRCS3 products collection>>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdf MSDS
pdf Datasheet

Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAP-SPh-189 Human SMAD7 Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAP-SPh-189
Gene Name SMAD7
Accession Number NM_005904
Gene ID 4092
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 1281 bp
Gene Alias CRCS3,MADH7,MADH8
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin
ORF Nucleotide Sequence ATGTTCAGGACCAAACGATCTGCGCTCGTCCGGCGTCTCTGGAGGAGCCGTGCGCCCGGCGGCGAGGACGAGGAGGAGGGCGCAGGGGGAGGTGGAGGAGGAGGCGAGCTGCGGGGAGAAGGGGCGACGGACAGCCGAGCGCATGGGGCCGGTGGCGGCGGCCCGGGCAGGGCTGGATGCTGCCTGGGCAAGGCGGTGCGAGGTGCCAAAGGTCACCACCATCCCCACCCGCCAGCCGCGGGCGCCGGCGCGGCCGGGGGCGCCGAGGCGGATCTGAAGGCGCTCACGCACTCGGTGCTCAAGAAACTGAAGGAGCGGCAGCTGGAGCTGCTGCTCCAGGCCGTGGAGTCCCGCGGCGGGACGCGCACCGCGTGCCTCCTGCTGCCCGGCCGCCTGGACTGCAGGCTGGGCCCGGGGGCGCCCGCCGGCGCGCAGCCTGCGCAGCCGCCCTCGTCCTACTCGCTCCCCCTCCTGCTGTGCAAAGTGTTCAGGTGGCCGGATCTCAGGCATTCCTCGGAAGTCAAGAGGCTGTGTTGCTGTGAATCTTACGGGAAGATCAACCCCGAGCTGGTGTGCTGCAACCCCCATCACCTTAGCCGACTCTGCGAACTAGAGTCTCCCCCCCCTCCTTACTCCAGATACCCGATGGATTTTCTCAAACCAACTGCAGACTGTCCAGATGCTGTGCCTTCCTCCGCTGAAACAGGGGGAACGAATTATCTGGCCCCTGGGGGGCTTTCAGATTCCCAACTTCTTCTGGAGCCTGGGGATCGGTCACACTGGTGCGTGGTGGCATACTGGGAGGAGAAGACGAGAGTGGGGAGGCTCTACTGTGTCCAGGAGCCCTCTCTGGATATCTTCTATGATCTACCTCAGGGGAATGGCTTTTGCCTCGGACAGCTCAATTCGGACAACAAGAGTCAGCTGGTGCAGAAGGTGCGGAGCAAAATCGGCTGCGGCATCCAGCTGACGCGGGAGGTGGATGGTGTGTGGGTGTACAACCGCAGCAGTTACCCCATCTTCATCAAGTCCGCCACACTGGACAACCCGGACTCCAGGACGCTGTTGGTACACAAGGTGTTCCCCGGTTTCTCCATCAAGGCTTTCGACTACGAGAAGGCGTACAGCCTGCAGCGGCCCAATGACCACGAGTTTATGCAGCAGCCGTGGACGGGCTTTACCGTGCAGATCAGCTTTGTGAAGGGCTGGGGCCAGTGCTACACCCGCCAGTTCATCAGCAGCTGCCCGTGCTGGCTAGAGGTCATCTTCAACAGCCGGTAG
ORF Protein Sequence MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNYLAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNSR

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T94695-Ab Anti-SMAD7 monoclonal antibody
    Target Antigen GM-Tg-g-T94695-Ag SMAD7 protein
    Cytokine cks-Tg-g-GM-T94695 SMAD family member 7 (SMAD7) protein & antibody
    ORF Viral Vector pGMLP001429 Human SMAD7 Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-049 Human SMAD7 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-189 Human SMAD7 Adenovirus plasmid
    ORF Viral Vector pGMPC000433 Human SMAD7 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP001429 Human SMAD7 Lentivirus particle
    ORF Viral Vector vGMLP-SPh-049 Human SMAD7 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-189 Human SMAD7 Adenovirus particle


    Target information

    Target ID GM-T94695
    Target Name SMAD7
    Gene Group Identifier
    （Target Gene ID in Homo species)         		4092
    Gene ID 100033853 (Equus caballus), 101088277 (Felis catus), 17131 (Mus musculus), 4092 (Homo sapiens)
    490570 (Canis lupus familiaris), 535916 (Bos taurus), 698338 (Macaca mulatta), 81516 (Rattus norvegicus)
    Gene Symbols & Synonyms SMAD7,Smad7,Madh7,CRCS3,MADH7,MADH8
    Target Alternative Names CRCS3,MAD homolog 7,MADH7,MADH8,Madh7,Mothers against DPP homolog 7,Mothers against DPP homolog 8),Mothers against decapentaplegic homolog 7,Mothers against decapentaplegic homolog 8 (MAD homolog 8,SMAD family member 7 (SMAD 7,SMAD7,Smad7,hSMAD7)
    Uniprot Accession O15105,O35253,O88406
    Additional SwissProt Accessions: O35253,O15105,O88406
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target, Cytokine Target
    Disease cancer
    Disease from KEGG TGF-beta signaling pathway, Hippo signaling pathway
    Gene Ensembl ENSECAG00000020583, ENSMUSG00000025880, ENSG00000101665, ENSCAFG00845017036, ENSBTAG00000012441, ENSMMUG00000056276
    Target Classification Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.