p70 S6K/RPS6KB1/S6K1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore p70 S6K/RPS6KB1/S6K1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]

Target ID GM-T94479
Target Name p70 S6K/RPS6KB1/S6K1
Gene Group ldentifer
（Target Gene ID in Homo species) 		6198
Gene ID 100057481 (Equus caballus), 101092561 (Felis catus), 404181 (Bos taurus), 480580 (Canis lupus familiaris)
6198 (Homo sapiens), 711979 (Macaca mulatta), 72508 (Mus musculus), 83840 (Rattus norvegicus)
Target Alternative Names 2610318I15Rik,70 kDa ribosomal protein S6 kinase 1 (P70S6K1,P70S6K1,PS6K,RPS6KB1,Ribosomal protein S6 kinase I,Ribosomal protein S6 kinase beta-1,Rps6kb1,S6K,S6K-beta-1,S6K1,STK14A,Serine/threonine-protein kinase 14A,p70 S6K,p70 S6K-alpha,p70 S6KA,p70 S6KA),p70 ribosomal S6 kinase alpha (p70 S6 kinase alpha,p70(S6K)-alpha,p70-S6K,p70-S6K 1,p70-S6K 1),p70-alpha,p70/85s6k,p70s6k
Uniprot Accession Q6TJY3,P23443,Q8BSK8,P67999
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, TGF-beta signaling pathway, Insulin resistance, Human cytomegalovirus infection, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer, Pancreatic cancer, Acute myeloid leukemia, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer
Gene Ensembl ENSECAG00000013890, ENSBTAG00000016851, ENSCAFG00845026236, ENSG00000108443, ENSMMUG00000019305, ENSMUSG00000020516
Target Classification Kinase, Tumor-associated antigen (TAA)


Pre-made viral vector of p70 S6K/RPS6KB1/S6K1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP001423Human RPS6KB1/p70 S6KA/p70(S6K)-alpha Lentivirus plasmidNM_0031616198HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLP005301Human RPS6KB1/p70 S6KA/p70(S6K)-alpha Lentivirus plasmidNM_001272043.16198HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLP005706Human RPS6KB1/p70 S6KA/p70(S6K)-alpha Lentivirus plasmidNM_003161.36198HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP001423Human RPS6KB1/p70 S6KA/p70(S6K)-alpha Lentivirus particleNM_0031616198HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLP005301Human RPS6KB1/p70 S6KA/p70(S6K)-alpha Lentivirus particleNM_001272043.16198HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLP005706Human RPS6KB1/p70 S6KA/p70(S6K)-alpha Lentivirus particleNM_003161.36198HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV001290Mouse Rps6kb1/2610318I15Rik/AA959758 Adeno-associate virus(AAV) plasmidNM_001114334.272508MouseAdeno-associate virus(AAV) plasmidmCherry3xflag (C-Terminal)CMVDetail
pGMLPm002997Mouse Rps6kb1/2610318I15Rik/AA959758 Lentivirus plasmidNM_00111433472508MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV001290Mouse Rps6kb1/2610318I15Rik/AA959758 Adeno-associate virus(AAV) particleNM_001114334.272508MouseAdeno-associate virus(AAV) particlemCherry3xflag (C-Terminal)CMVDetail
vGMLPm002997Mouse Rps6kb1/2610318I15Rik/AA959758 Lentivirus particleNM_00111433472508MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


p70 S6K/RPS6KB1/S6K1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo6198Pre-made Human RPS6KB1/S6K/PS6K siRNA oligo Duplex6198HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo83840Pre-made Rat Rps6kb1/p70 S6K-alpha siRNA oligo Duplex83840RatIn-vitro grade; in-vivo gradeDetail
pGMoligo72508Pre-made Mouse Rps6kb1/S6K/S6K1 siRNA oligo Duplex72508MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo711979Pre-made Cynomolgus/Rhesus macaque RPS6KB1 siRNA oligo Duplex711979Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101092561Pre-made Cat/Feline RPS6KB1 siRNA oligo Duplex101092561Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo480580Pre-made Dog/Canine RPS6KB1 siRNA oligo Duplex480580Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo404181Pre-made Bovines/Cattle RPS6KB1/S6K1 siRNA oligo Duplex404181Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100057481Pre-made Equine/Horse RPS6KB1 siRNA oligo Duplex100057481Equine/HorseIn-vitro grade; in-vivo gradeDetail


p70 S6K/RPS6KB1/S6K1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T94479-AbHumanAnti-Human p70 S6K/RPS6KB1/S6K1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T94479-AbRatAnti-Rat p70 S6K/RPS6KB1/S6K1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T94479-AbMouseAnti-Mouse p70 S6K/RPS6KB1/S6K1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T94479-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque p70 S6K/RPS6KB1/S6K1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T94479-AbCat/FelineAnti-Cat/Feline p70 S6K/RPS6KB1/S6K1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T94479-AbDog/CanineAnti-Dog/Canine p70 S6K/RPS6KB1/S6K1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T94479-AbBovines/CattleAnti-Bovines/Cattle p70 S6K/RPS6KB1/S6K1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T94479-AbEquine/HorseAnti-Equine/Horse p70 S6K/RPS6KB1/S6K1 monoclonal antibodymabTherapeutics Target antibodyDetail


p70 S6K/RPS6KB1/S6K1 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T94479-AgHumanHuman p70 S6K/RPS6KB1/S6K1 recombinant proteinMammalian cellDetail
GM-Tg-rg-T94479-AgRatRat p70 S6K/RPS6KB1/S6K1 recombinant proteinMammalian cellDetail
GM-Tg-mg-T94479-AgMouseMouse p70 S6K/RPS6KB1/S6K1 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T94479-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque p70 S6K/RPS6KB1/S6K1 recombinant proteinMammalian cellDetail
GM-Tg-felg-T94479-AgCat/FelineCat/Feline p70 S6K/RPS6KB1/S6K1 recombinant proteinMammalian cellDetail
GM-Tg-cang-T94479-AgDog/CanineDog/Canine p70 S6K/RPS6KB1/S6K1 recombinant proteinMammalian cellDetail
GM-Tg-bovg-T94479-AgBovines/CattleBovines/Cattle p70 S6K/RPS6KB1/S6K1 recombinant proteinMammalian cellDetail
GM-Tg-equg-T94479-AgEquine/HorseEquine/Horse p70 S6K/RPS6KB1/S6K1 recombinant proteinMammalian cellDetail