Human RPS6KB1/p70 S6KA/p70(S6K)-alpha ORF/cDNA clone-Lentivirus plasmid (NM_003161.3)

Cat. No.: pGMLP005706
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human RPS6KB1/p70 S6KA/p70(S6K)-alpha Lentiviral expression plasmid for RPS6KB1 lentivirus packaging, RPS6KB1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP005706
Gene Name RPS6KB1
Accession Number NM_003161.3
Gene ID 6198
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1578 bp
Gene Alias p70 S6KA,p70(S6K)-alpha,p70-alpha,p70-S6K,PS6K,S6K,S6K-beta-1,S6K1,STK14A
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAGGCGACGAAGGAGGCGGGACGGCTTTTACCCAGCCCCGGACTTCCGAGACAGGGAAGCTGAGGACATGGCAGGAGTGTTTGACATAGACCTGGACCAGCCAGAGGACGCGGGCTCTGAGGATGAGCTGGAGGAGGGGGGTCAGTTAAATGAAAGCATGGACCATGGGGGAGTTGGACCATATGAACTTGGCATGGAACATTGTGAGAAATTTGAAATCTCAGAAACTAGTGTGAACAGAGGGCCAGAAAAAATCAGACCAGAATGTTTTGAGCTACTTCGGGTACTTGGTAAAGGGGGCTATGGAAAGGTTTTTCAAGTACGAAAAGTAACAGGAGCAAATACTGGGAAAATATTTGCCATGAAGGTGCTTAAAAAGGCAATGATAGTAAGAAATGCTAAAGATACAGCTCATACAAAAGCAGAACGGAATATTCTGGAGGAAGTAAAGCATCCCTTCATCGTGGATTTAATTTATGCCTTTCAGACTGGTGGAAAACTCTACCTCATCCTTGAGTATCTCAGTGGAGGAGAACTATTTATGCAGTTAGAAAGAGAGGGAATATTTATGGAAGACACTGCCTGCTTTTACTTGGCAGAAATCTCCATGGCTTTGGGGCATTTACATCAAAAGGGGATCATCTACAGAGACCTGAAGCCGGAGAATATCATGCTTAATCACCAAGGTCATGTGAAACTAACAGACTTTGGACTATGCAAAGAATCTATTCATGATGGAACAGTCACACACACATTTTGTGGAACAATAGAATACATGGCCCCTGAAATCTTGATGAGAAGTGGCCACAATCGTGCTGTGGATTGGTGGAGTTTGGGAGCATTAATGTATGACATGCTGACTGGAGCACCCCCATTCACTGGGGAGAATAGAAAGAAAACAATTGACAAAATCCTCAAATGTAAACTCAATTTGCCTCCCTACCTCACACAAGAAGCCAGAGATCTGCTTAAAAAGCTGCTGAAAAGAAATGCTGCTTCTCGTCTGGGAGCTGGTCCTGGGGACGCTGGAGAAGTTCAAGCTCATCCATTCTTTAGACACATTAACTGGGAAGAACTTCTGGCTCGAAAGGTGGAGCCCCCCTTTAAACCTCTGTTGCAATCTGAAGAGGATGTAAGTCAGTTTGATTCCAAGTTTACACGTCAGACACCTGTCGACAGCCCAGATGACTCAACTCTCAGTGAAAGTGCCAATCAGGTCTTTCTGGGTTTTACATATGTGGCTCCATCTGTACTTGAAAGTGTGAAAGAAAAGTTTTCCTTTGAACCAAAAATCCGATCACCTCGAAGATTTATTGGCAGCCCACGAACACCTGTCAGCCCAGTCAAATTTTCTCCTGGGGATTTCTGGGGAAGAGGTGCTTCGGCCAGCACAGCAAATCCTCAGACACCTGTGGAATACCCAATGGAAACAAGTGGCATAGAGCAGATGGATGTGACAATGAGTGGGGAAGCATCGGCACCACTTCCAATACGACAGCCGAACTCTGGGCCATACAAAAAACAAGCTTTTCCCATGATCTCCAAACGGCCAGAGCACCTGCGTATGAATCTATGA
ORF Protein Sequence MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T94479-Ab Anti-S6K1 monoclonal antibody
    Target Antigen GM-Tg-g-T94479-Ag S6K1/RPS6KB1 protein
    ORF Viral Vector pGMLP001423 Human RPS6KB1 Lentivirus plasmid
    ORF Viral Vector pGMLP005301 Human RPS6KB1 Lentivirus plasmid
    ORF Viral Vector pGMLP005706 Human RPS6KB1 Lentivirus plasmid
    ORF Viral Vector vGMLP001423 Human RPS6KB1 Lentivirus particle
    ORF Viral Vector vGMLP005301 Human RPS6KB1 Lentivirus particle
    ORF Viral Vector vGMLP005706 Human RPS6KB1 Lentivirus particle


    Target information

    Target ID GM-T94479
    Target Name p70 S6K/RPS6KB1/S6K1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		6198
    Gene ID 100057481 (Equus caballus), 101092561 (Felis catus), 404181 (Bos taurus), 480580 (Canis lupus familiaris)
    6198 (Homo sapiens), 711979 (Macaca mulatta), 72508 (Mus musculus), 83840 (Rattus norvegicus)
    Gene Symbols & Synonyms RPS6KB1,Rps6kb1,S6K1,S6K,PS6K,STK14A,p70-S6K,p70 S6KA,p70-alpha,S6K-beta-1,p70(S6K)-alpha,p70s6k,P70S6K1,p70-S6K 1,p70/85s6k,2610318I15Rik,p70 S6K-alpha
    Target Alternative Names 2610318I15Rik,70 kDa ribosomal protein S6 kinase 1 (P70S6K1,P70S6K1,PS6K,RPS6KB1,Ribosomal protein S6 kinase I,Ribosomal protein S6 kinase beta-1,Rps6kb1,S6K,S6K-beta-1,S6K1,STK14A,Serine/threonine-protein kinase 14A,p70 S6K,p70 S6K-alpha,p70 S6KA,p70 S6KA),p70 ribosomal S6 kinase alpha (p70 S6 kinase alpha,p70(S6K)-alpha,p70-S6K,p70-S6K 1,p70-S6K 1),p70-alpha,p70/85s6k,p70s6k
    Uniprot Accession P23443,P67999,Q6TJY3,Q8BSK8
    Additional SwissProt Accessions: Q6TJY3,P23443,Q8BSK8,P67999
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, TGF-beta signaling pathway, Insulin resistance, Human cytomegalovirus infection, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer, Pancreatic cancer, Acute myeloid leukemia, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer
    Gene Ensembl ENSECAG00000013890, ENSBTAG00000016851, ENSCAFG00845026236, ENSG00000108443, ENSMMUG00000019305, ENSMUSG00000020516
    Target Classification Kinase, Tumor-associated antigen (TAA)


    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.