Recombinant multi-species p70 S6K/RPS6KB1/S6K1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine p70 S6K/RPS6KB1/S6K1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
The Alternative Names of target: 2610318I15Rik,70 kDa ribosomal protein S6 kinase 1 (P70S6K1,P70S6K1,PS6K,RPS6KB1,Ribosomal protein S6 kinase I,Ribosomal protein S6 kinase beta-1,Rps6kb1,S6K,S6K-beta-1,S6K1,STK14A,Serine/threonine-protein kinase 14A,p70 S6K,p70 S6K-alpha,p70 S6KA,p70 S6KA),p70 ribosomal S6 kinase alpha (p70 S6 kinase alpha,p70(S6K)-alpha,p70-S6K,p70-S6K 1,p70-S6K 1),p70-alpha,p70/85s6k,p70s6k
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T94479-Ag-1/ GM-Tg-hg-T94479-Ag-2 | Human p70 S6K/RPS6KB1/S6K1 protein | Human |
| GM-Tg-rg-T94479-Ag-1/ GM-Tg-rg-T94479-Ag-2 | Rat p70 S6K/RPS6KB1/S6K1 protein | Rat |
| GM-Tg-mg-T94479-Ag-1/ GM-Tg-mg-T94479-Ag-2 | Mouse p70 S6K/RPS6KB1/S6K1 protein | Mouse |
| GM-Tg-cynog-T94479-Ag-1/ GM-Tg-cynog-T94479-Ag-2 | Cynomolgus/Rhesus macaque p70 S6K/RPS6KB1/S6K1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T94479-Ag-1/ GM-Tg-felg-T94479-Ag-2 | Feline p70 S6K/RPS6KB1/S6K1 protein | Feline |
| GM-Tg-cang-T94479-Ag-1/ GM-Tg-cang-T94479-Ag-2 | Canine p70 S6K/RPS6KB1/S6K1 protein | Canine |
| GM-Tg-bovg-T94479-Ag-1/ GM-Tg-bovg-T94479-Ag-2 | Bovine p70 S6K/RPS6KB1/S6K1 protein | Bovine |
| GM-Tg-equg-T94479-Ag-1/ GM-Tg-equg-T94479-Ag-2 | Equine p70 S6K/RPS6KB1/S6K1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T94479-Ag-1/ GM-Tg-hg-T94479-Ag-2;
GM-Tg-rg-T94479-Ag-1/ GM-Tg-rg-T94479-Ag-2;
GM-Tg-mg-T94479-Ag-1/ GM-Tg-mg-T94479-Ag-2; GM-Tg-cynog-T94479-Ag-1/ GM-Tg-cynog-T94479-Ag-2; GM-Tg-felg-T94479-Ag-1/ GM-Tg-felg-T94479-Ag-2; GM-Tg-cang-T94479-Ag-1/ GM-Tg-cang-T94479-Ag-2; GM-Tg-bovg-T94479-Ag-1/ GM-Tg-bovg-T94479-Ag-2; GM-Tg-equg-T94479-Ag-1/ GM-Tg-equg-T94479-Ag-2 |
| Products Name | p70 S6K/RPS6KB1/S6K1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | p70 S6K/RPS6KB1/S6K1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine p70 S6K/RPS6KB1/S6K1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.