Explore IL-24/IL24 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T93450
|
| Target Name |
IL-24/IL24
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
11009
|
| Gene ID |
100055675 (Equus caballus), 101095874 (Felis catus), 11009 (Homo sapiens), 170819 (Rattus norvegicus)
526285 (Bos taurus), 609213 (Canis lupus familiaris), 694541 (Macaca mulatta), 93672 (Mus musculus)
|
| Target Alternative Names |
C49A,FISP,IL-24,IL10B,IL24,If2e,Il24,Interleukin-24,MDA7,MOB5,Mda-7,Mda7,Melanoma differentiation-associated gene 7 protein (MDA-7),ST16,St16,Suppression of tumorigenicity 16 protein
|
| Uniprot Accession |
Q13007,Q9JI24,Q925S4
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, JAK-STAT signaling pathway
|
| Gene Ensembl |
ENSECAG00000012240, ENSG00000162892, ENSBTAG00000007851, ENSCAFG00845001393, ENSMUSG00000026420
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of IL-24/IL24 cDNA Clones/ORF Plasmid
IL-24/IL24 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo11009 | Pre-made Human IL24/C49A/FISP siRNA oligo Duplex | 11009 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo170819 | Pre-made Rat Il24/If2e/Mda7 siRNA oligo Duplex | 170819 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo93672 | Pre-made Mouse Il24/FISP/If2e siRNA oligo Duplex | 93672 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694541 | Pre-made Cynomolgus/Rhesus macaque IL24 siRNA oligo Duplex | 694541 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095874 | Pre-made Cat/Feline IL24 siRNA oligo Duplex | 101095874 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609213 | Pre-made Dog/Canine IL24 siRNA oligo Duplex | 609213 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo526285 | Pre-made Bovines/Cattle IL24 siRNA oligo Duplex | 526285 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055675 | Pre-made Equine/Horse IL24 siRNA oligo Duplex | 100055675 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-24/IL24 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T93450-Ab | Human | Anti-Human IL-24/IL24 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T93450-Ab | Rat | Anti-Rat IL-24/IL24 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T93450-Ab | Mouse | Anti-Mouse IL-24/IL24 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T93450-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-24/IL24 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T93450-Ab | Cat/Feline | Anti-Cat/Feline IL-24/IL24 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T93450-Ab | Dog/Canine | Anti-Dog/Canine IL-24/IL24 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T93450-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-24/IL24 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T93450-Ab | Equine/Horse | Anti-Equine/Horse IL-24/IL24 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-24/IL24 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T93450-Ag | Human | Human IL-24/IL24 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T93450-Ag | Rat | Rat IL-24/IL24 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T93450-Ag | Mouse | Mouse IL-24/IL24 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T93450-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-24/IL24 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T93450-Ag | Cat/Feline | Cat/Feline IL-24/IL24 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T93450-Ag | Dog/Canine | Dog/Canine IL-24/IL24 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T93450-Ag | Bovines/Cattle | Bovines/Cattle IL-24/IL24 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T93450-Ag | Equine/Horse | Equine/Horse IL-24/IL24 recombinant protein | Mammalian cell | Detail |
