Recombinant multi-species IL-24/IL24 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-24/IL24 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
The Alternative Names of target: C49A,FISP,IL-24,IL10B,IL24,If2e,Il24,Interleukin-24,MDA7,MOB5,Mda-7,Mda7,Melanoma differentiation-associated gene 7 protein (MDA-7),ST16,St16,Suppression of tumorigenicity 16 protein

Target products collectionGo to IL-24/IL24 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T93450-Ag-1/ GM-Tg-hg-T93450-Ag-2 Human IL-24/IL24 protein Human
GM-Tg-rg-T93450-Ag-1/ GM-Tg-rg-T93450-Ag-2 Rat IL-24/IL24 protein Rat
GM-Tg-mg-T93450-Ag-1/ GM-Tg-mg-T93450-Ag-2 Mouse IL-24/IL24 protein Mouse
GM-Tg-cynog-T93450-Ag-1/ GM-Tg-cynog-T93450-Ag-2 Cynomolgus/Rhesus macaque IL-24/IL24 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T93450-Ag-1/ GM-Tg-felg-T93450-Ag-2 Feline IL-24/IL24 protein Feline
GM-Tg-cang-T93450-Ag-1/ GM-Tg-cang-T93450-Ag-2 Canine IL-24/IL24 protein Canine
GM-Tg-bovg-T93450-Ag-1/ GM-Tg-bovg-T93450-Ag-2 Bovine IL-24/IL24 protein Bovine
GM-Tg-equg-T93450-Ag-1/ GM-Tg-equg-T93450-Ag-2 Equine IL-24/IL24 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T93450-Ag-1/ GM-Tg-hg-T93450-Ag-2; GM-Tg-rg-T93450-Ag-1/ GM-Tg-rg-T93450-Ag-2;
GM-Tg-mg-T93450-Ag-1/ GM-Tg-mg-T93450-Ag-2; GM-Tg-cynog-T93450-Ag-1/ GM-Tg-cynog-T93450-Ag-2;
GM-Tg-felg-T93450-Ag-1/ GM-Tg-felg-T93450-Ag-2; GM-Tg-cang-T93450-Ag-1/ GM-Tg-cang-T93450-Ag-2;
GM-Tg-bovg-T93450-Ag-1/ GM-Tg-bovg-T93450-Ag-2; GM-Tg-equg-T93450-Ag-1/ GM-Tg-equg-T93450-Ag-2
Products Name IL-24/IL24 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IL-24/IL24
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-24/IL24 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.