SIRT3 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore SIRT3 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019]

Target ID GM-T91959
Target Name SIRT3
Gene Group ldentifer
（Target Gene ID in Homo species) 		23410
Gene ID 100054908 (Equus caballus), 101087609 (Felis catus), 23410 (Homo sapiens), 293615 (Rattus norvegicus)
475933 (Canis lupus familiaris), 614027 (Bos taurus), 64384 (Mus musculus), 720737 (Macaca mulatta)
Target Alternative Names 2310003L23Rik,NAD-dependent protein deacetylase sirtuin-3,NAD-dependent protein delactylase sirtuin-3,Regulatory protein SIR2 homolog 3,SIR2-like protein 3,SIR2L3,SIRT3,Sir2l3,Sirt3,hSIRT3,mitochondrial
Uniprot Accession Q9NTG7,Q8R104
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG Metabolic pathways, Central carbon metabolism in cancer
Gene Ensembl ENSECAG00000003330, ENSG00000142082, ENSCAFG00845028357, ENSBTAG00000002044, ENSMUSG00000025486, ENSMMUG00000008490


Pre-made viral vector of SIRT3 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP002811Human SIRT3/SIR2L3 Lentivirus plasmidNM_01223923410HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAD000249Human SIRT3/SIR2L3 Adenovirus plasmidNM_012239.523410HumanAdenovirus plasmidNullNullCMVDetail
vGMAD000464Human SIRT3/SIR2L3 Adenovirus particleNM_012239.523410HumanAdenovirus particleNullNullCMVDetail
vGMAD000249Human SIRT3/SIR2L3 Adenovirus particleNM_012239.523410HumanAdenovirus particleNullNullCMVDetail
vGMLV001438Human SIRT3/SIR2L3 Lentivirus particleNM_012239.623410HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV000991Human SIRT3/SIR2L3 Lentivirus particleNM_001370310.123410HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLP002811Human SIRT3/SIR2L3 Lentivirus particleNM_01223923410HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMPC000393Human SIRT3/SIR2L3 Mammalian (Non-Viral Vector) plasmidNM_012239.523410HumanMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMPC000237Human SIRT3/SIR2L3 Mammalian (Non-Viral Vector) plasmidNM_012239.523410HumanMammalian (Non-Viral Vector) plasmidZsGreenHA (C-Terminal)CMVDetail
pGMAD000464Human SIRT3/SIR2L3 Adenovirus plasmidNM_012239.523410HumanAdenovirus plasmidNullNullCMVDetail
pGMPC000866Human SIRT3/SIR2L3 Mammalian (Non-Viral Vector) plasmidNM_012239.623410HumanMammalian (Non-Viral Vector) plasmidNull3xflag (C-Terminal)CMVDetail
pGMLV000991Human SIRT3/SIR2L3 Lentivirus plasmidNM_001370310.123410HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV001438Human SIRT3/SIR2L3 Lentivirus plasmidNM_012239.623410HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLV001050Rat Sirt3 Lentivirus particleNM_001106313.2293615RatLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV001049Rat Sirt3 Lentivirus particleNM_001106313.2293615RatLentivirus particleNull3xflag (C-Terminal)CMVDetail
pGMLV001049Rat Sirt3 Lentivirus plasmidNM_001106313.2293615RatLentivirus plasmidNull3xflag (C-Terminal)CMVDetail
vGMLV001773Rat Sirt3 Lentivirus particleNM_001106313293615RatLentivirus particleNull3xflag (C-Terminal)CMVDetail
pGMLV001050Rat Sirt3 Lentivirus plasmidNM_001106313.2293615RatLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAD000849Rat Sirt3 Adenovirus particleNM_001106313.2293615RatAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
vGMAAV000011Rat Sirt3 Adeno-associate virus(AAV) particleNM_001106313.2293615RatAdeno-associate virus(AAV) particleGFP3xflag (C-Terminal)CMVDetail
pGMAAV001659Rat Sirt3 Adeno-associate virus(AAV) plasmidNM_001106313.2293615RatAdeno-associate virus(AAV) plasmidZsGreenNullCMVDetail
pGMAD000849Rat Sirt3 Adenovirus plasmidNM_001106313.2293615RatAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMAAV000011Rat Sirt3 Adeno-associate virus(AAV) plasmidNM_001106313.2293615RatAdeno-associate virus(AAV) plasmidGFP3xflag (C-Terminal)CMVDetail
vGMAAV001659Rat Sirt3 Adeno-associate virus(AAV) particleNM_001106313.2293615RatAdeno-associate virus(AAV) particleZsGreenNullCMVDetail
pGMLV001773Rat Sirt3 Lentivirus plasmidNM_001106313293615RatLentivirus plasmidNull3xflag (C-Terminal)CMVDetail
vGMAAV000487Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) particleNM_00117780464384MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV000316Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) particleNM_001127351.164384MouseAdeno-associate virus(AAV) particleGFP3xflag (C-Terminal)hSynDetail
vGMAAV000256Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) particleNM_001177804.164384MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)hSynDetail
vGMAAV000991Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) particleNM_001177804.164384MouseAdeno-associate virus(AAV) particlemCherryHA (C-Terminal)TBGDetail
vGMAAV001018Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) particleNM_001177804.164384MouseAdeno-associate virus(AAV) particlemCherryHA (C-Terminal)TBGDetail
vGMAAV001140Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) particleNM_00117780464384MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)SM22aDetail
vGMAAV001274Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) particleNM_001177804.164384MouseAdeno-associate virus(AAV) particleEGFP3xflag (C-Terminal)CTNTDetail
vGMAD000828Mouse Sirt3/2310003L23Rik/AI848213 Adenovirus particleNM_00117780464384MouseAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
pGMLV000395Mouse Sirt3/2310003L23Rik/AI848213 Lentivirus plasmidNM_001127351.164384MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV000826Mouse Sirt3/2310003L23Rik/AI848213 Lentivirus plasmidNM_001127351.164384MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAD000084Mouse Sirt3/2310003L23Rik/AI848213 Adenovirus particleNM_012239.564384MouseAdenovirus particleNullNullCMVDetail
vGMLPm001256Mouse Sirt3/2310003L23Rik/AI848213 Lentivirus particleNM_00117780464384MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV000826Mouse Sirt3/2310003L23Rik/AI848213 Lentivirus particleNM_001127351.164384MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV001290Mouse sirt3/2310003L23Rik/AI848213 Lentivirus particleNM_001177804.164384MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV001140Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) plasmidNM_00117780464384MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)SM22aDetail
pGMAD000828Mouse Sirt3/2310003L23Rik/AI848213 Adenovirus plasmidNM_00117780464384MouseAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMAAV000256Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) plasmidNM_001177804.164384MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)hSynDetail
pGMAAV000316Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) plasmidNM_001127351.164384MouseAdeno-associate virus(AAV) plasmidGFP3xflag (C-Terminal)hSynDetail
pGMAAV000487Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) plasmidNM_00117780464384MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV000991Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) plasmidNM_001177804.164384MouseAdeno-associate virus(AAV) plasmidmCherryHA (C-Terminal)TBGDetail
pGMAAV001018Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) plasmidNM_001177804.164384MouseAdeno-associate virus(AAV) plasmidmCherryHA (C-Terminal)TBGDetail
pGMAAV001274Mouse Sirt3/2310003L23Rik/AI848213 Adeno-associate virus(AAV) plasmidNM_001177804.164384MouseAdeno-associate virus(AAV) plasmidEGFP3xflag (C-Terminal)CTNTDetail
pGMAD000084Mouse Sirt3/2310003L23Rik/AI848213 Adenovirus plasmidNM_012239.564384MouseAdenovirus plasmidNullNullCMVDetail
pGMLPm001256Mouse Sirt3/2310003L23Rik/AI848213 Lentivirus plasmidNM_00117780464384MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV001290Mouse sirt3/2310003L23Rik/AI848213 Lentivirus plasmidNM_001177804.164384MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV000371Mouse Sirt3/2310003L23Rik/AI848213 Lentivirus plasmidNM_00117780464384MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC004789Mouse Sirt3/2310003L23Rik/Sir2l3 Mammalian (Non-Viral Vector) plasmidNM_001177804.164384MouseMammalian (Non-Viral Vector) plasmidNullMYC (C-Terminal)CMVDetail
vGMLV000371Mouse Sirt3/2310003L23Rik/AI848213 Lentivirus particleNM_00117780464384MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV000395Mouse Sirt3/2310003L23Rik/AI848213 Lentivirus particleNM_001127351.164384MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAD000097Cattle SIRT3 Adenovirus particleNM_001206669.1614027CattleAdenovirus particleNull3xflag (C-Terminal)CMVDetail
pGMAD000097Cattle SIRT3 Adenovirus plasmidNM_001206669.1614027CattleAdenovirus plasmidNull3xflag (C-Terminal)CMVDetail


SIRT3 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo23410Pre-made Human SIRT3/SIR2L3 siRNA oligo Duplex23410HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo293615Pre-made Rat Sirt3 siRNA oligo Duplex293615RatIn-vitro grade; in-vivo gradeDetail
pGMoligo64384Pre-made Mouse Sirt3/Sir2l3/2310003L23Rik siRNA oligo Duplex64384MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo720737Pre-made Cynomolgus/Rhesus macaque SIRT3 siRNA oligo Duplex720737Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101087609Pre-made Cat/Feline SIRT3 siRNA oligo Duplex101087609Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo475933Pre-made Dog/Canine SIRT3 siRNA oligo Duplex475933Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo614027Pre-made Bovines/Cattle SIRT3 siRNA oligo Duplex614027Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100054908Pre-made Equine/Horse SIRT3 siRNA oligo Duplex100054908Equine/HorseIn-vitro grade; in-vivo gradeDetail


SIRT3 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T91959-AbHumanAnti-Human SIRT3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T91959-AbRatAnti-Rat SIRT3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T91959-AbMouseAnti-Mouse SIRT3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T91959-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque SIRT3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T91959-AbCat/FelineAnti-Cat/Feline SIRT3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T91959-AbDog/CanineAnti-Dog/Canine SIRT3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T91959-AbBovines/CattleAnti-Bovines/Cattle SIRT3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T91959-AbEquine/HorseAnti-Equine/Horse SIRT3 monoclonal antibodymabTherapeutics Target antibodyDetail


SIRT3 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T91959-AgHumanHuman SIRT3 recombinant proteinMammalian cellDetail
GM-Tg-rg-T91959-AgRatRat SIRT3 recombinant proteinMammalian cellDetail
GM-Tg-mg-T91959-AgMouseMouse SIRT3 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T91959-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque SIRT3 recombinant proteinMammalian cellDetail
GM-Tg-felg-T91959-AgCat/FelineCat/Feline SIRT3 recombinant proteinMammalian cellDetail
GM-Tg-cang-T91959-AgDog/CanineDog/Canine SIRT3 recombinant proteinMammalian cellDetail
GM-Tg-bovg-T91959-AgBovines/CattleBovines/Cattle SIRT3 recombinant proteinMammalian cellDetail
GM-Tg-equg-T91959-AgEquine/HorseEquine/Horse SIRT3 recombinant proteinMammalian cellDetail