Explore IGF2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
| Target ID |
GM-T90572
|
| Target Name |
IGF2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3481
|
| Gene ID |
100034182 (Equus caballus), 101093644 (Felis catus), 16002 (Mus musculus), 24483 (Rattus norvegicus)
281240 (Bos taurus), 3481 (Homo sapiens), 483664 (Canis lupus familiaris), 710802 (Macaca mulatta)
|
| Target Alternative Names |
C11orf43,GRDF,IGF-II,IGF2,IGFII,Igf-2,Igf-II,Igf2,Insulin-like growth factor 2,Insulin-like growth factor II (IGF-II),M6pr,Mpr,PP9974,Peg2,RNIGF2,SRS3,Somatomedin-A,T3M-11-derived growth factor
|
| Uniprot Accession |
P51459,P09535,P01346,P07456,P01344
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, INN Index, Cytokine Target
|
| Disease |
cancer, Ovary Cancer
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Hepatocellular carcinoma
|
| Gene Ensembl |
ENSECAG00000028346, ENSMUSG00000048583, ENSBTAG00000013066, ENSG00000167244, ENSCAFG00845011017, ENSMMUG00000047449
|
Pre-made viral vector of IGF2 cDNA Clones/ORF Plasmid
IGF2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3481 | Pre-made Human IGF2/GRDF/SRS3 siRNA oligo Duplex | 3481 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24483 | Pre-made Rat Igf2/IGFII/RNIGF2 siRNA oligo Duplex | 24483 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16002 | Pre-made Mouse Igf2/Mpr/M6pr siRNA oligo Duplex | 16002 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710802 | Pre-made Cynomolgus/Rhesus macaque IGF2 siRNA oligo Duplex | 710802 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093644 | Pre-made Cat/Feline IGF2 siRNA oligo Duplex | 101093644 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483664 | Pre-made Dog/Canine IGF2 siRNA oligo Duplex | 483664 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281240 | Pre-made Bovines/Cattle IGF2 siRNA oligo Duplex | 281240 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034182 | Pre-made Equine/Horse IGF2/IGF-II siRNA oligo Duplex | 100034182 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IGF2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T90572-Ab | Human | Anti-Human IGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T90572-Ab | Rat | Anti-Rat IGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T90572-Ab | Mouse | Anti-Mouse IGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T90572-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T90572-Ab | Cat/Feline | Anti-Cat/Feline IGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T90572-Ab | Dog/Canine | Anti-Dog/Canine IGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T90572-Ab | Bovines/Cattle | Anti-Bovines/Cattle IGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T90572-Ab | Equine/Horse | Anti-Equine/Horse IGF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IGF2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T90572-Ag | Human | Human IGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T90572-Ag | Rat | Rat IGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T90572-Ag | Mouse | Mouse IGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T90572-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T90572-Ag | Cat/Feline | Cat/Feline IGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T90572-Ag | Dog/Canine | Dog/Canine IGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T90572-Ag | Bovines/Cattle | Bovines/Cattle IGF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T90572-Ag | Equine/Horse | Equine/Horse IGF2 recombinant protein | Mammalian cell | Detail |
