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Human IGF2/FLJ22066/FLJ44734 ORF/cDNA clone-Adenovirus particle (BC000531)
Cat. No.: vGMAP000466
Pre-made Human IGF2/FLJ22066/FLJ44734 Adenovirus for IGF2 overexpression in-vitro and in-vivo. The IGF2 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified IGF2-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.
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Product information
| Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
| vGMAP000466 | Human IGF2 Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
| 5E+10PFU (1E+10pfu/ml×5ml) | |||
| 1E+11PFU (1E+10pfu/ml×10ml) | |||
| Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMAP000466 |
| Gene Name | IGF2 |
| Accession Number | BC000531 |
| Gene ID | 3481 |
| Species | Human |
| Product Type | Adenovirus particle (overexpression) |
| Insert Length | 543 bp |
| Gene Alias | FLJ22066,FLJ44734,INSIGF,pp9974 |
| Fluorescent Reporter | GFP |
| Mammalian Cell Selection | Null |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | EF1 |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGGGAATCCCAATGGGGAAGTCGATGCTGGTGCTTCTCACCTTCTTGGCCTTCGCCTCGTGCTGCATTGCTGCTTACCGCCCCAGTGAGACCCTGTGCGGCGGGGAGCTGGTGGACACCCTCCAGTTCGTCTGTGGGGACCGCGGCTTCTACTTCAGCAGGCCCGCAAGCCGTGTGAGCCGTCGCAGCCGTGGCATCGTTGAGGAGTGCTGTTTCCGCAGCTGTGACCTGGCCCTCCTGGAGACGTACTGTGCTACCCCCGCCAAGTCCGAGAGGGACGTGTCGACCCCTCCGACCGTGCTTCCGGACAACTTCCCCAGATACCCCGTGGGCAAGTTCTTCCAATATGACACCTGGAAGCAGTCCACCCAGCGCCTGCGCAGGGGCCTGCCTGCCCTCCTGCGTGCCCGCCGGGGTCACGTGCTCGCCAAGGAGCTCGAGGCGTTCAGGGAGGCCAAACGTCACCGTCCCCTGATTGCTCTACCCACCCAAGACCCCGCCCACGGGGGCGCCCCCCCAGAGATGGCCAGCAATCGGAAGTGA |
| ORF Protein Sequence | MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Biosimilar | GMP-Bios-ab-634 | Pre-Made Xentuzumab biosimilar, Whole mAb, Anti-IGF1;IGF2 Antibody: Anti-IGF/IGF-I/IGFI/MGF;C11orf43/GRDF/IGF-II/PP9974/SRS3 therapeutic antibody |
| Biosimilar | GMP-Bios-ab-160 | Pre-Made Dusigitumab biosimilar, Whole mAb, Anti-IGF1;IGF2 Antibody: Anti-IGF/IGF-I/IGFI/MGF;C11orf43/GRDF/IGF-II/PP9974/SRS3 therapeutic antibody |
| Target Antibody | GM-Tg-g-T90572-Ab | Anti-IGF2/ C11orf43/ GRDF functional antibody |
| Target Antigen | GM-Tg-g-T90572-Ag | IGF2 protein |
| Cytokine | cks-Tg-g-GM-T90572 | insulin-like growth factor 2 (IGF2) protein & antibody |
| ORF Viral Vector | pGMLV000393 | Human IGF2 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000475 | Human IGF2 Lentivirus plasmid |
| ORF Viral Vector | pGMAP000466 | Human IGF2 Adenovirus plasmid |
| ORF Viral Vector | vGMLV000393 | Human IGF2 Lentivirus particle |
| ORF Viral Vector | vGMLV000475 | Human IGF2 Lentivirus particle |
| ORF Viral Vector | vGMAP000466 | Human IGF2 Adenovirus particle |
Target information
| Target ID | GM-T90572 |
| Target Name | IGF2 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
3481 |
| Gene ID |
100034182 (Equus caballus), 101093644 (Felis catus), 16002 (Mus musculus), 24483 (Rattus norvegicus) 281240 (Bos taurus), 3481 (Homo sapiens), 483664 (Canis lupus familiaris), 710802 (Macaca mulatta) |
| Gene Symbols & Synonyms | IGF2,Igf2,IGF-II,Mpr,M6pr,Peg2,Igf-2,Igf-II,IGFII,RNIGF2,GRDF,SRS3,PP9974,C11orf43 |
| Target Alternative Names | C11orf43,GRDF,IGF-II,IGF2,IGFII,Igf-2,Igf-II,Igf2,Insulin-like growth factor 2,Insulin-like growth factor II (IGF-II),M6pr,Mpr,PP9974,Peg2,RNIGF2,SRS3,Somatomedin-A,T3M-11-derived growth factor |
| Uniprot Accession |
P01344,P01346,P07456,P09535,P51459
Additional SwissProt Accessions: P51459,P09535,P01346,P07456,P01344 |
| Uniprot Entry Name | |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, INN Index, Cytokine Target |
| Disease | cancer, Ovary Cancer |
| Disease from KEGG | MAPK signaling pathway, Ras signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Hepatocellular carcinoma |
| Gene Ensembl | ENSECAG00000028346, ENSMUSG00000048583, ENSBTAG00000013066, ENSG00000167244, ENSCAFG00845011017, ENSMMUG00000047449 |
| Target Classification |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.