NR0B2 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore NR0B2 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008]

Target ID GM-T89859
Target Name NR0B2
Gene Group ldentifer
(Target Gene ID in Homo species)
8431
Gene ID 101081062 (Felis catus), 117274 (Rattus norvegicus), 138915016 (Equus caballus), 23957 (Mus musculus)
514770 (Bos taurus), 612125 (Canis lupus familiaris), 715170 (Macaca mulatta), 8431 (Homo sapiens)
Target Alternative Names NR0B2,Nr0b2,Nuclear receptor subfamily 0 group B member 2,Orphan nuclear receptor SHP,SHP,SHP-1,SHP1,Shp,Shp1,Small heterodimer partner
Uniprot Accession P97947,Q62227,Q15466
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG Bile secretion
Gene Ensembl ENSMUSG00000037583, ENSBTAG00000014848, ENSCAFG00845011182, ENSMMUG00000010291, ENSG00000131910
Target Classification Tumor-associated antigen (TAA)


Pre-made viral vector of NR0B2 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP003773Human NR0B2/SHP/SHP1 Lentivirus plasmidNM_0219698431HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP003773Human NR0B2/SHP/SHP1 Lentivirus particleNM_0219698431HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV001841Mouse Nr0b2/SHP/SHP-1 Adeno-associate virus(AAV) plasmidNM_011850.323957MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)TBGDetail
pGMLPm003778Mouse Nr0b2/SHP/SHP-1 Lentivirus plasmidNM_01185023957MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV001841Mouse Nr0b2/SHP/SHP-1 Adeno-associate virus(AAV) particleNM_011850.323957MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)TBGDetail
vGMLPm003778Mouse Nr0b2/SHP/SHP-1 Lentivirus particleNM_01185023957MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


NR0B2 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo8431Pre-made Human NR0B2/SHP/SHP1 siRNA oligo Duplex8431HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo117274Pre-made Rat Nr0b2/Shp siRNA oligo Duplex117274RatIn-vitro grade; in-vivo gradeDetail
pGMoligo23957Pre-made Mouse Nr0b2/SHP/Shp1 siRNA oligo Duplex23957MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo715170Pre-made Cynomolgus/Rhesus macaque NR0B2 siRNA oligo Duplex715170Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101081062Pre-made Cat/Feline NR0B2 siRNA oligo Duplex101081062Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo612125Pre-made Dog/Canine NR0B2 siRNA oligo Duplex612125Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo514770Pre-made Bovines/Cattle NR0B2 siRNA oligo Duplex514770Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo138915016Pre-made Equine/Horse NR0B2 siRNA oligo Duplex138915016Equine/HorseIn-vitro grade; in-vivo gradeDetail


NR0B2 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T89859-AbHumanAnti-Human NR0B2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T89859-AbRatAnti-Rat NR0B2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T89859-AbMouseAnti-Mouse NR0B2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T89859-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque NR0B2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T89859-AbCat/FelineAnti-Cat/Feline NR0B2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T89859-AbDog/CanineAnti-Dog/Canine NR0B2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T89859-AbBovines/CattleAnti-Bovines/Cattle NR0B2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T89859-AbEquine/HorseAnti-Equine/Horse NR0B2 monoclonal antibodymabTherapeutics Target antibodyDetail


NR0B2 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T89859-AgHumanHuman NR0B2 recombinant proteinMammalian cellDetail
GM-Tg-rg-T89859-AgRatRat NR0B2 recombinant proteinMammalian cellDetail
GM-Tg-mg-T89859-AgMouseMouse NR0B2 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T89859-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque NR0B2 recombinant proteinMammalian cellDetail
GM-Tg-felg-T89859-AgCat/FelineCat/Feline NR0B2 recombinant proteinMammalian cellDetail
GM-Tg-cang-T89859-AgDog/CanineDog/Canine NR0B2 recombinant proteinMammalian cellDetail
GM-Tg-bovg-T89859-AgBovines/CattleBovines/Cattle NR0B2 recombinant proteinMammalian cellDetail
GM-Tg-equg-T89859-AgEquine/HorseEquine/Horse NR0B2 recombinant proteinMammalian cellDetail