Explore TREM-1/CD354/TREM1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]
| Target ID |
GM-T89780
|
| Target Name |
TREM-1/CD354/TREM1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
54210
|
| Gene ID |
100054285 (Equus caballus), 101099551 (Felis catus), 301229 (Rattus norvegicus), 404547 (Bos taurus)
54210 (Homo sapiens), 58217 (Mus musculus), 608994 (Canis lupus familiaris), 693558 (Macaca mulatta)
|
| Target Alternative Names |
CD354,TREM-1,TREM1,Trem1,Triggering receptor expressed on monocytes 1,Triggering receptor expressed on myeloid cells 1
|
| Uniprot Accession |
Q6QUN5,Q9NP99,Q9JKE2
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000017436, ENSBTAG00000017593, ENSG00000124731, ENSMUSG00000042265, ENSCAFG00845015313, ENSMMUG00000003674
|
| Target Classification |
Pathway
|
Pre-made viral vector of TREM-1/CD354/TREM1 cDNA Clones/ORF Plasmid
TREM-1/CD354/TREM1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo54210 | Pre-made Human TREM1/CD354/TREM-1 siRNA oligo Duplex | 54210 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo301229 | Pre-made Rat Trem1 siRNA oligo Duplex | 301229 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58217 | Pre-made Mouse Trem1 siRNA oligo Duplex | 58217 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693558 | Pre-made Cynomolgus/Rhesus macaque TREM1 siRNA oligo Duplex | 693558 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099551 | Pre-made Cat/Feline TREM1 siRNA oligo Duplex | 101099551 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608994 | Pre-made Dog/Canine TREM1/TREM-1 siRNA oligo Duplex | 608994 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo404547 | Pre-made Bovines/Cattle TREM1/TREM-1 siRNA oligo Duplex | 404547 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054285 | Pre-made Equine/Horse TREM1 siRNA oligo Duplex | 100054285 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TREM-1/CD354/TREM1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T89780-Ab | Human | Anti-Human TREM-1/CD354/TREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T89780-Ab | Rat | Anti-Rat TREM-1/CD354/TREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T89780-Ab | Mouse | Anti-Mouse TREM-1/CD354/TREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T89780-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TREM-1/CD354/TREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T89780-Ab | Cat/Feline | Anti-Cat/Feline TREM-1/CD354/TREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T89780-Ab | Dog/Canine | Anti-Dog/Canine TREM-1/CD354/TREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T89780-Ab | Bovines/Cattle | Anti-Bovines/Cattle TREM-1/CD354/TREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T89780-Ab | Equine/Horse | Anti-Equine/Horse TREM-1/CD354/TREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TREM-1/CD354/TREM1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T89780-Ag | Human | Human TREM-1/CD354/TREM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T89780-Ag | Rat | Rat TREM-1/CD354/TREM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T89780-Ag | Mouse | Mouse TREM-1/CD354/TREM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T89780-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TREM-1/CD354/TREM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T89780-Ag | Cat/Feline | Cat/Feline TREM-1/CD354/TREM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T89780-Ag | Dog/Canine | Dog/Canine TREM-1/CD354/TREM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T89780-Ag | Bovines/Cattle | Bovines/Cattle TREM-1/CD354/TREM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T89780-Ag | Equine/Horse | Equine/Horse TREM-1/CD354/TREM1 VLP (virus-like particle) | HEK293 | Products Developing |
