KLF4 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein
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Target
sublocation: Introcelluar Protein.
This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
| Target ID | GM-T81916 |
| Target Name | KLF4 |
|
Gene Group ldentifer （Target Gene ID in Homo species) |
9314 |
| Gene ID |
100054047 (Equus caballus), 100379626 (Felis catus), 114505 (Rattus norvegicus), 16600 (Mus musculus) 481657 (Canis lupus familiaris), 520842 (Bos taurus), 711169 (Macaca mulatta), 9314 (Homo sapiens) |
| Target Alternative Names | EZF,Epithelial zinc finger protein EZF,GKLF,Gklf,Gut-enriched krueppel-like factor,KLF4,Klf4,Krueppel-like factor 4,Zie |
| Uniprot Accession | Q60793,O43474 |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | cancer |
| Disease from KEGG | Signaling pathways regulating pluripotency of stem cells, Chemical carcinogenesis - receptor activation |
| Gene Ensembl | ENSECAG00000010613, ENSMUSG00000003032, ENSCAFG00845011624, ENSBTAG00000020355, ENSMMUG00000006088, ENSG00000136826 |
| Target Classification | Tumor-associated antigen (TAA) |
Pre-made viral vector of KLF4 cDNA Clones/ORF Plasmid
| Cat No. | Product Name | NMID | GeneID | Species | Type | Marker | Fusion Tag | Promoter | Detail |
|---|---|---|---|---|---|---|---|---|---|
| pGMLV000247 | Human KLF4/EZF/GKLF Lentivirus plasmid | NM_004235.4 | 9314 | Human | Lentivirus plasmid | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| vGMLV000247 | Human KLF4/EZF/GKLF Lentivirus particle | NM_004235.4 | 9314 | Human | Lentivirus particle | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| vGMAD001331 | Human KLF4/EZF/GKLF Adenovirus particle | NM_001314052.2 | 9314 | Human | Adenovirus particle | EGFP | HA (C-Terminal) | EF1 | Detail |
| vGMAD000806 | Human KLF4/EZF/GKLF Adenovirus particle | NM_004235.6 | 9314 | Human | Adenovirus particle | Null | 3xflag (C-Terminal) | CMV | Detail |
| vGMAD000164 | Human KLF4/EZF/GKLF Adenovirus particle | NM_004235.4 | 9314 | Human | Adenovirus particle | Null | 3xflag (C-Terminal) | CMV | Detail |
| vGMLV002425 | Human KLF4/EZF/GKLF Lentivirus particle | NM_001314052.2 | 9314 | Human | Lentivirus particle | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| vGMLV002172 | Human KLF4/EZF/GKLF Lentivirus particle | NM_001314052.2 | 9314 | Human | Lentivirus particle | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMPC001122 | Human KLF4/EZF/GKLF Mammalian (Non-Viral Vector) plasmid | NM_001314052.2 | 9314 | Human | Mammalian (Non-Viral Vector) plasmid | Firefly luciferase | Null | CMV | Detail |
| pGMAD000806 | Human KLF4/EZF/GKLF Adenovirus plasmid | NM_004235.6 | 9314 | Human | Adenovirus plasmid | Null | 3xflag (C-Terminal) | CMV | Detail |
| pGMAD001331 | Human KLF4/EZF/GKLF Adenovirus plasmid | NM_001314052.2 | 9314 | Human | Adenovirus plasmid | EGFP | HA (C-Terminal) | EF1 | Detail |
| pGMLV002172 | Human KLF4/EZF/GKLF Lentivirus plasmid | NM_001314052.2 | 9314 | Human | Lentivirus plasmid | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMLV002425 | Human KLF4/EZF/GKLF Lentivirus plasmid | NM_001314052.2 | 9314 | Human | Lentivirus plasmid | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMAD000164 | Human KLF4/EZF/GKLF Adenovirus plasmid | NM_004235.4 | 9314 | Human | Adenovirus plasmid | Null | 3xflag (C-Terminal) | CMV | Detail |
| vGMAD000361 | Rat Klf4/GKLF Adenovirus particle | NM_053713 | 114505 | Rat | Adenovirus particle | Null | Null | CMV | Detail |
| pGMAAV000090 | Rat Klf4/GKLF Adeno-associate virus(AAV) plasmid | NM_053713 | 114505 | Rat | Adeno-associate virus(AAV) plasmid | GFP | 3xflag (C-Terminal) | CMV | Detail |
| vGMAAV000090 | Rat Klf4/GKLF Adeno-associate virus(AAV) particle | NM_053713 | 114505 | Rat | Adeno-associate virus(AAV) particle | GFP | 3xflag (C-Terminal) | CMV | Detail |
| pGMAD000361 | Rat Klf4/GKLF Adenovirus plasmid | NM_053713 | 114505 | Rat | Adenovirus plasmid | Null | Null | CMV | Detail |
| vGMAAV001603 | Mouse Klf4/EZF/Gklf Adeno-associate virus(AAV) particle | NM_010637.3 | 16600 | Mouse | Adeno-associate virus(AAV) particle | Null | 3xflag (C-Terminal) | FABP4 | Detail |
| vGMAAV000259 | Mouse Klf4/EZF/Gklf Adeno-associate virus(AAV) particle | NM_010637.3 | 16600 | Mouse | Adeno-associate virus(AAV) particle | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| vGMAD001602 | Mouse Klf4/EZF/Gklf Adenovirus particle | NM_010637.3 | 16600 | Mouse | Adenovirus particle | EGFP | 3xHA (C-Terminal) | EF1 | Detail |
| vGMAD001599 | Mouse Klf4/EZF/Gklf Adenovirus particle | NM_010637.3 | 16600 | Mouse | Adenovirus particle | Null | 3xflag (C-Terminal) | CMV | Detail |
| pGMAD000237 | Mouse Klf4/EZF/Gklf Adenovirus plasmid | NM_010637.3 | 16600 | Mouse | Adenovirus plasmid | GFP | 3xflag (C-Terminal) | EF1 | Detail |
| vGMAD000237 | Mouse Klf4/EZF/Gklf Adenovirus particle | NM_010637.3 | 16600 | Mouse | Adenovirus particle | GFP | 3xflag (C-Terminal) | EF1 | Detail |
| pGMAD001599 | Mouse Klf4/EZF/Gklf Adenovirus plasmid | NM_010637.3 | 16600 | Mouse | Adenovirus plasmid | Null | 3xflag (C-Terminal) | CMV | Detail |
| vGMLV000981 | Mouse Klf4/EZF/Gklf Lentivirus particle | NM_010637.3 | 16600 | Mouse | Lentivirus particle | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMLV000981 | Mouse Klf4/EZF/Gklf Lentivirus plasmid | NM_010637.3 | 16600 | Mouse | Lentivirus plasmid | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMAAV001858 | Mouse Klf4/EZF/Gklf Adeno-associate virus(AAV) plasmid | NM_010637.3 | 16600 | Mouse | Adeno-associate virus(AAV) plasmid | ZsGreen | 3xflag (C-Terminal) | F4/80 | Detail |
| pGMAAV001603 | Mouse Klf4/EZF/Gklf Adeno-associate virus(AAV) plasmid | NM_010637.3 | 16600 | Mouse | Adeno-associate virus(AAV) plasmid | Null | 3xflag (C-Terminal) | FABP4 | Detail |
| pGMAAV000259 | Mouse Klf4/EZF/Gklf Adeno-associate virus(AAV) plasmid | NM_010637.3 | 16600 | Mouse | Adeno-associate virus(AAV) plasmid | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMAD001602 | Mouse Klf4/EZF/Gklf Adenovirus plasmid | NM_010637.3 | 16600 | Mouse | Adenovirus plasmid | EGFP | 3xHA (C-Terminal) | EF1 | Detail |
| vGMAAV001858 | Mouse Klf4/EZF/Gklf Adeno-associate virus(AAV) particle | NM_010637.3 | 16600 | Mouse | Adeno-associate virus(AAV) particle | ZsGreen | 3xflag (C-Terminal) | F4/80 | Detail |
KLF4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|---|---|---|---|---|
| pGMoligo9314 | Pre-made Human KLF4/EZF/GKLF siRNA oligo Duplex | 9314 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114505 | Pre-made Rat Klf4/GKLF siRNA oligo Duplex | 114505 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16600 | Pre-made Mouse Klf4/EZF/Zie siRNA oligo Duplex | 16600 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711169 | Pre-made Cynomolgus/Rhesus macaque KLF4 siRNA oligo Duplex | 711169 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100379626 | Pre-made Cat/Feline KLF4 siRNA oligo Duplex | 100379626 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481657 | Pre-made Dog/Canine KLF4 siRNA oligo Duplex | 481657 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo520842 | Pre-made Bovines/Cattle KLF4 siRNA oligo Duplex | 520842 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054047 | Pre-made Equine/Horse KLF4 siRNA oligo Duplex | 100054047 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KLF4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|---|---|---|---|---|
| GM-Tg-hg-T81916-Ab | Human | Anti-Human KLF4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T81916-Ab | Rat | Anti-Rat KLF4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T81916-Ab | Mouse | Anti-Mouse KLF4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T81916-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KLF4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T81916-Ab | Cat/Feline | Anti-Cat/Feline KLF4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T81916-Ab | Dog/Canine | Anti-Dog/Canine KLF4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T81916-Ab | Bovines/Cattle | Anti-Bovines/Cattle KLF4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T81916-Ab | Equine/Horse | Anti-Equine/Horse KLF4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
KLF4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|---|---|---|---|
| GM-Tg-hg-T81916-Ag | Human | Human KLF4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T81916-Ag | Rat | Rat KLF4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T81916-Ag | Mouse | Mouse KLF4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T81916-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KLF4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T81916-Ag | Cat/Feline | Cat/Feline KLF4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T81916-Ag | Dog/Canine | Dog/Canine KLF4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T81916-Ag | Bovines/Cattle | Bovines/Cattle KLF4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T81916-Ag | Equine/Horse | Equine/Horse KLF4 recombinant protein | Mammalian cell | Detail |